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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Erythrobacter litoralis (strain HTCC2594)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciELIT314225:GHLE-2587-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:ELI_12710
OrganismiErythrobacter litoralis (strain HTCC2594)
Taxonomic identifieri314225 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesErythrobacteraceaeErythrobacter
Proteomesi
  • UP000008808 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 477477Exodeoxyribonuclease 7 large subunitPRO_0000303786Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi314225.ELI_12710.

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229266.
KOiK03601.
OMAiILERGFV.
OrthoDBiEOG64R65J.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2N6Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDLIAQSRA GDNAEPLSVS ALSQMLKRTV EDRFGYVRLR GELSGVKRAA
60 70 80 90 100
SGHMYCSLKD EKAVIDGVMW KGTTARLAFQ PEDGLEVIAT GKLTTYPGRS
110 120 130 140 150
KYQIVLESLE MAGEGALLAL LEKTRQRLEA EGLFARDRKR PLPFLPRTIG
160 170 180 190 200
VVTSPTGAVI RDILHRLADR FPSHVLVWPV LVQGQGAAEQ VSAAIRGFGA
210 220 230 240 250
IKAGGEVPRP DLLIVARGGG SIEDLWSFNE EMVVRAIADS PIPVISAVGH
260 270 280 290 300
ETDTTLADYA ADRRAPTPTA AAEIAVPVKG ELAATLNDYA ARQQRGVLRP
310 320 330 340 350
LSLGRERLEA RVQRLPTIET LLQPQAQKLD ERVERLRGAL RDRAAKGREA
360 370 380 390 400
LATQRLSPTM LQRAEREARR KLDQVRLAPA LVERRAARDG ERLAGLSRVL
410 420 430 440 450
ATLNPRAPLE RGYALVRDAD GKLVRAKGEA TKQARLAVEF ADGSLDVVPA
460 470
GKAAAAPKRV KKSPPPGTSG AQEDLFG
Length:477
Mass (Da):51,620
Last modified:February 7, 2006 - v1
Checksum:iB552CD0CA3C3E6AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000157 Genomic DNA. Translation: ABC64634.1.
RefSeqiWP_011415456.1. NC_007722.1.

Genome annotation databases

EnsemblBacteriaiABC64634; ABC64634; ELI_12710.
KEGGieli:ELI_12710.
PATRICi21862243. VBIEryLit102657_2534.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000157 Genomic DNA. Translation: ABC64634.1.
RefSeqiWP_011415456.1. NC_007722.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi314225.ELI_12710.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC64634; ABC64634; ELI_12710.
KEGGieli:ELI_12710.
PATRICi21862243. VBIEryLit102657_2534.

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229266.
KOiK03601.
OMAiILERGFV.
OrthoDBiEOG64R65J.

Enzyme and pathway databases

BioCyciELIT314225:GHLE-2587-MONOMER.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Erythrobacter litoralis HTCC2594."
    Oh H.M., Giovannoni S.J., Ferriera S., Johnson J., Cho J.C.
    J. Bacteriol. 191:2419-2420(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HTCC2594.

Entry informationi

Entry nameiEX7L_ERYLH
AccessioniPrimary (citable) accession number: Q2N6Q7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: February 7, 2006
Last modified: November 11, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.