Q2N6I7 (RSMG_ERYLH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase G
EC=2.1.1.170

Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase

Gene names

Name:	rsmG
Ordered Locus Names:	ELI_13060

Organism

Erythrobacter litoralis (strain HTCC2594) [Complete proteome] [HAMAP]

Taxonomic identifier

314225 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Erythrobacteraceae › Erythrobacter › Erythrobacter litoralis

Protein attributes

Sequence length	207 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA By similarity. HAMAP-Rule MF_00074
Catalytic activity	S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA. HAMAP-Rule MF_00074
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00074.
Sequence similarities	Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	rRNA (guanine-N7)-methylation Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	rRNA (guanine-N7-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 207	207	Ribosomal RNA small subunit methyltransferase G HAMAP-Rule MF_00074		PRO_1000010144
Regions
	Region	126 – 127	2	S-adenosyl-L-methionine binding By similarity
Sites
	Binding site	75	1	S-adenosyl-L-methionine; via carbonyl oxygen By similarity
	Binding site	80	1	S-adenosyl-L-methionine; via carbonyl oxygen By similarity
	Binding site	140	1	S-adenosyl-L-methionine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2N6I7 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 6F930171E4E55948	FASTA	207	22,845
	10 20 30 40 50 60 MIATEEQARA FVAERCDAAG MERIEALVAA LRSENERQNL VSKGSLGEVW QRHIADSAQL 70 80 90 100 110 120 LDHVSRETGL WLDLGSGAGF PGLVVAAMQP EKPVLLVESR RKRVEWLTDM VKALKLENCD 130 140 150 160 170 180 VAGMRLELLE AREAGVISAR AFAPLEKLLR LSARFSTDTT TWVLPKGRSA AQELQGVSRK 190 200 WQKLFHVEQS VTSEEAAILV GRGRAKT

References

[1]	"Complete genome sequence of Erythrobacter litoralis HTCC2594." Oh H.M., Giovannoni S.J., Ferriera S., Johnson J., Cho J.C. J. Bacteriol. 191:2419-2420(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HTCC2594.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000157 Genomic DNA. Translation: ABC64704.1.
RefSeq	YP_459501.1. NC_007722.1.
3D structure databases
ProteinModelPortal	Q2N6I7.
ModBase	Search...
Protein-protein interaction databases
STRING	314225.ELI_13060.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABC64704; ABC64704; ELI_13060.
GeneID	3870234.
KEGG	eli:ELI_13060.
PATRIC	21862383. VBIEryLit102657_2604.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0357.
HOGENOM	HOG000221015.
KO	K03501.
OMA	FHKGRDY.
ProtClustDB	CLSK844134.
Enzyme and pathway databases
BioCyc	ELIT314225:GHLE-2657-MONOMER.
Family and domain databases
HAMAP	MF_00074. 16SrRNA_methyltr_G.
InterPro	IPR003682. rRNA_ssu_MeTfrase_G. [Graphical view]
Pfam	PF02527. GidB. 1 hit. [Graphical view]
PIRSF	PIRSF003078. GidB. 1 hit.
TIGRFAMs	TIGR00138. gidB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RSMG_ERYLH

Accession

Primary (citable) accession number: Q2N6I7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 7, 2006
Last modified:	May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program