ID   Q2N6G6_ERYLH            Unreviewed;       531 AA.
AC   Q2N6G6;
DT   07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT   07-FEB-2006, sequence version 1.
DT   27-MAR-2024, entry version 90.
DE   RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE            EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN   OrderedLocusNames=ELI_13165 {ECO:0000313|EMBL:ABC64725.1};
OS   Erythrobacter litoralis (strain HTCC2594).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Erythrobacteraceae; Erythrobacter/Porphyrobacter group; Erythrobacter.
OX   NCBI_TaxID=314225 {ECO:0000313|EMBL:ABC64725.1, ECO:0000313|Proteomes:UP000008808};
RN   [1] {ECO:0000313|Proteomes:UP000008808}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2594 {ECO:0000313|Proteomes:UP000008808};
RX   PubMed=19168610; DOI=10.1128/JB.00026-09;
RA   Oh H.M., Giovannoni S.J., Ferriera S., Johnson J., Cho J.C.;
RT   "Complete genome sequence of Erythrobacter litoralis HTCC2594.";
RL   J. Bacteriol. 191:2419-2420(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC         (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC         diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR   EMBL; CP000157; ABC64725.1; -; Genomic_DNA.
DR   RefSeq; WP_011415547.1; NC_007722.1.
DR   AlphaFoldDB; Q2N6G6; -.
DR   STRING; 314225.ELI_13165; -.
DR   KEGG; eli:ELI_13165; -.
DR   eggNOG; COG1793; Bacteria.
DR   HOGENOM; CLU_005138_6_2_5; -.
DR   OrthoDB; 9767858at2; -.
DR   Proteomes; UP000008808; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR   CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR   Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR   PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ABC64725.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008808}.
FT   DOMAIN          302..432
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
SQ   SEQUENCE   531 AA;  59993 MW;  348ECB50C43DC3A0 CRC64;
     MQAFADLIDA LVYTRSRNEK LRLIAAYLRE TPDPDRGWAL AALTDGLDFP AVKSSAIRTI
     MKERIDPVLW TLSRDFVGDT AETASLLWPA PDSDVTPPPS VSEVVDLLSK MTRQSVLTEL
     PALLDRLDPS GRYALLKIAT GAMRIGVSSR LAKVAFAQAF GVDVEDVEEY WHGLEPPYEE
     LFAWAADGAD PPDTENKPTF RPFMLAHPLE DTVVDMADYA AEWKWDGIRV QLVHAGGETR
     IYSRSGDDIS RTFPEMVDAL QVPAVLDGEL LVRGDAQGGE AGGAASFNAL QQRLGRKTVS
     KKMLSESPAF VRLYDALIIE GEDLRDQPWE RRRDHLERFV PRLPDSHFDL STIVDARDFE
     HLAEIREGTR EDAIEGLMLK RRDSPYIAGR KTGLWYKWKR DPLLVDCVLM YAQRGSGKRS
     SFYSDYTFGC WDGDPDKGAE LLPVGKAYSG FTDEELKKLD RLVRQNTLNR FGPVREVERT
     LVFEVAFDSV HTSKRHKSGL AMRFPRIHRI RWDKPVHEAD RLQTLKAMIQ D
//