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Q2N379 (Q2N379_9CALI) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length510 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). SAAS SAAS001205

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2401Magnesium PDB 4LQ3 PDB 4LQ9
Metal binding3441Magnesium PDB 4LQ3 PDB 4LQ9
Metal binding3451Magnesium; via carbonyl oxygen PDB 4LQ3 PDB 4LQ9
Metal binding3891Magnesium; via carbonyl oxygen PDB 4LQ3 PDB 4LQ9

Experimental info

Non-terminal residue11 EMBL ABC59067.1

Sequences

Sequence LengthMass (Da)Tools
Q2N379 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: DE89880415A7AD72

FASTA51056,844
        10         20         30         40         50         60 
GDDSKGTYCG APILGPGSAP KLSTKTKFWR SSTTPLPPGT YEPAYLGGKD PRVKGGPSLQ 

        70         80         90        100        110        120 
QVMRDQLKPF TEPRGKPPKP SVLEAAKKTI INVLEQTIDP PEKWSFTQAC ASLDKTTSSG 

       130        140        150        160        170        180 
HPHHMRKNDC WNGESFTGKL ADQASKANLM FEEGKNMTPV YTGALKDELV KTDKIYGKIK 

       190        200        210        220        230        240 
KRLLWGSDLA TMIRCARAFG GLMDELKAHC VTLPIRVGMN MNEDGPIIFE RHSRYKYHYD 

       250        260        270        280        290        300 
ADYSRWDSTQ QRAVLAAALE IMVKFSSEPH LAQVVAEDLL SPSVVDVGDF KISINEGLPS 

       310        320        330        340        350        360 
GVPCTSQWNS IAHWLLTLCA LSEVTNLSPD IIQANSLFSF YGDDEIVSTD IKLDPEKLTA 

       370        380        390        400        410        420 
KLKEYGLKPT RPDKTEGPLV ISEDLNGLTF LRRTVTRDPA GWFGKLEQSS ILRQMYWTRG 

       430        440        450        460        470        480 
PNHEDPSETM IPHSQRPIQL MSLLGEAALH GPAFYSKISK LVIAELKEGG MDFYVPRQEP 

       490        500        510 
MFRWMRFSDL STWEGDRNLA PSFVNEDGVE 

« Hide

References

[1]"Emergence of a new norovirus genotype II.4 variant associated with global outbreaks of gastroenteritis."
Bull R.A., Tu E.T., McIver C.J., Rawlinson W.D., White P.A.
J. Clin. Microbiol. 44:327-333(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Sydney348/97O EMBL ABC59067.1.
[2]"Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase."
Tarantino D., Pezzullo M., Mastrangelo E., Croci R., Rohayem J., Robel I., Bolognesi M., Milani M.
Antiviral Res. 102:23-28(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.04 ANGSTROMS) OF 3-510 IN COMPLEX WITH MAGNESIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ078829 Genomic RNA. Translation: ABC59067.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4LQ3X-ray2.60A3-510[»]
4LQ9X-ray2.04A3-510[»]
ProteinModelPortalQ2N379.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004004. Helic/Pol/Pept_Calicivir-typ.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
[Graphical view]
PfamPF00680. RdRP_1. 1 hit.
[Graphical view]
PRINTSPR00918. CALICVIRUSNS.
PROSITEPS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2N379_9CALI
AccessionPrimary (citable) accession number: Q2N379
Entry history
Integrated into UniProtKB/TrEMBL: February 7, 2006
Last sequence update: February 7, 2006
Last modified: July 9, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)