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Protein
Submitted name:

ICP8

Gene

UL29

Organism
Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. single-stranded DNA binding Source: InterPro

GO - Biological processi

  1. DNA replication Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-bindingImported

Names & Taxonomyi

Protein namesi
Submitted name:
ICP8Imported
Submitted name:
Single-stranded DNA-binding proteinImported
Submitted name:
UL29Imported
Gene namesi
Name:UL29Imported
OrganismiHuman herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)Imported
Taxonomic identifieri10298 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

GO - Cellular componenti

  1. host cell nucleus Source: InterPro
Complete GO annotation...

Family & Domainsi

Family and domain databases

InterProiIPR000635. Viral_ssDNA-bd.
[Graphical view]
PfamiPF00747. Viral_DNA_bp. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2MGU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKPKTATT IKVPPGPLGY VYARACPSEG IELLALLSAR SGDADVAVAP
60 70 80 90 100
LVVGLTVESG FEANVAVVVG SRTTGLGGTA VSLKLTPSHY SSSVYVFHGG
110 120 130 140 150
RHLDPSTQAP NLTRLCERAR RHFGFSDYTP RPGDLKHETT GEALCERLGL
160 170 180 190 200
DPDRALLYLV VTEGFKEAVC INNTFLHLGG SDKVTIGGAE VHRIPVYPLQ
210 220 230 240 250
LFMPDFSRVI AEPFNANHRS IGENFTYPLP FFNRPLNRLL FEAVVGPAAV
260 270 280 290 300
ALRCRNVDAV ARAAAHLAFD ENHEGAALPA DITFTAFEAS QGKTPRGGRD
310 320 330 340 350
GGGKGPAGGF EQRLASVMAG DAALALESIV SMAVFDEPPT DISAWPLCEG
360 370 380 390 400
QDTAAARANA VGAYLARAAG LVGAMVFSTN SALHLTEVDD AGPADPKDHS
410 420 430 440 450
KPSFYRFFLV PGTHVAANPQ VDREGHVVPG FEGRPTAPLV GGTQEFAGEH
460 470 480 490 500
LAMLCGFSPA LLAKMLFYLE RCDGGVIVGR QEMDVFRYVA DSNQTDVPCN
510 520 530 540 550
LCTFDTRHAC VHTTLMRLRA RHPKFASAAR GAIGVFGTMN SMYSDCDVLG
560 570 580 590 600
NYAAFSALKR ADGSETARTI MQETYRAATE RVMAELETLQ YVDQAVPTAM
610 620 630 640 650
GRLETIITNR EALHTVVNNV RQVVDREVEQ LMRNLVEGRN FKFRDGLGEA
660 670 680 690 700
NHAMSLTLDP YACGPCPLLQ LLGRRSNLAV YQDLALSQCH GVFAGQSVEG
710 720 730 740 750
RNFRNQFQPV LRRRVMDMFN NGFLSAKTLT VALSEGAAIC APSLTAGQTA
760 770 780 790 800
PAESSFEGDV ARVTLGFPKE LRVKSRVLFA GASANASEAA KARVASLQSA
810 820 830 840 850
YQKPDKRVDI LLGPLGFLLK QFHAAIFPNG KPPGSNQPNP QWFWTALQRN
860 870 880 890 900
QLPARLLSRE DIETIAFIKK FSLDYGAINF INLAPNNVSE LAMYYMANQI
910 920 930 940 950
LRYCDHSTYF INTLTAIIAG SRRPPSVQAA AAWSAQGGAG LEAGARALMD
960 970 980 990 1000
AVDAHPGAWT SMFASCNLLR PVMAARPMVV LGLSISKYYG MAGNDRVFQA
1010 1020 1030 1040 1050
GNWASLMGGK NACPLLIFDR TRKFVLACPR AGFVCAASSL GGGAHESSLC
1060 1070 1080 1090 1100
EQLRGIISEG GAAVASSVFV ATVKSLGPRT QQLQIEDWLA LLEDEYLSEE
1110 1120 1130 1140 1150
MMELTARALE RGNGEWSTDA ALEVAHEAEA LVSQLGNAGE VFNFGDFGCE
1160 1170 1180 1190
DDNATPFGGP GAPGPAFAGR KRAFHGDDPF GEGPPDKKGD LTLDML
Length:1,196
Mass (Da):128,288
Last modified:February 21, 2006 - v1
Checksum:i3A0EE0B53108894B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU734772 Genomic DNA. Translation: ADD60076.1.
HM585512 Genomic DNA. Translation: ADM23568.1.
HM585513 Genomic DNA. Translation: ADM23643.1.
HM585515 Genomic DNA. Translation: ADM23794.1.
JN400093 Genomic DNA. Translation: AER37613.1.
JN420338 Genomic DNA. Translation: AER37753.1.
JN420341 Genomic DNA. Translation: AER37967.1.
AB247574 Genomic DNA. Translation: BAE78516.1.
AB247575 Genomic DNA. Translation: BAE78517.1.
AB247576 Genomic DNA. Translation: BAE78518.1.
AB247578 Genomic DNA. Translation: BAE78520.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU734772 Genomic DNA. Translation: ADD60076.1.
HM585512 Genomic DNA. Translation: ADM23568.1.
HM585513 Genomic DNA. Translation: ADM23643.1.
HM585515 Genomic DNA. Translation: ADM23794.1.
JN400093 Genomic DNA. Translation: AER37613.1.
JN420338 Genomic DNA. Translation: AER37753.1.
JN420341 Genomic DNA. Translation: AER37967.1.
AB247574 Genomic DNA. Translation: BAE78516.1.
AB247575 Genomic DNA. Translation: BAE78517.1.
AB247576 Genomic DNA. Translation: BAE78518.1.
AB247578 Genomic DNA. Translation: BAE78520.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000635. Viral_ssDNA-bd.
[Graphical view]
PfamiPF00747. Viral_DNA_bp. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Analysis of genetic stability of essential genes in clinically isolated Herpes Simplex Virus 1."
    Suzuki M., Kobayashi N., Takahashi K., Honda R., Hirooka J., Okuda T., Yoshida Y., Hama Y., Kawana T., Shiraki K.
    Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BBY-V-1801Imported, KBS-C-1783Imported, KBS-V-1782Imported and YMS-1732Imported.
  2. "Sequence variability in clinical and laboratory isolates of herpes simplex virus 1 reveals new mutations."
    Szpara M.L., Parsons L., Enquist L.W.
    J. Virol. 84:5303-5313(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H129Imported.
  3. "Evolution of sexually transmitted and sexually transmissible human herpesviruses."
    Davison A.J.
    Ann. N. Y. Acad. Sci. 1230:E37-E49(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: R62Imported, S23Imported and S25Imported.
  4. "Multiplex sequencing of seven ocular herpes simplex virus type-1 genomes: phylogeny, sequence variability, and SNP distribution."
    Kolb A.W., Adams M., Cabot E.L., Craven M., Brandt C.R.
    Invest. Ophthalmol. Vis. Sci. 52:9061-9073(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 134Imported, CJ311Imported and CJ970Imported.
  5. Davison A.J.
    Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: R62Imported, S23Imported and S25Imported.

Entry informationi

Entry nameiQ2MGU6_HHV1
AccessioniPrimary (citable) accession number: Q2MGU6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 21, 2006
Last sequence update: February 21, 2006
Last modified: October 1, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.