ID Q2MGT9_RANTA Unreviewed; 229 AA. AC Q2MGT9; DT 21-FEB-2006, integrated into UniProtKB/TrEMBL. DT 21-FEB-2006, sequence version 1. DT 14-DEC-2011, entry version 31. DE RecName: Full=Sex-determining region Y protein; GN Name=SRY; OS Rangifer tarandus (Reindeer) (Cervus tarandus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Cervidae; Odocoileinae; Rangifer. OX NCBI_TaxID=9870; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Liver; RA Wada K., Nishibori M., Yokohama M.; RT "Sry gene in Cervidae."; RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Transcriptional regulator that controls a genetic switch CC in male development (By similarity). CC -!- SIMILARITY: Belongs to the SRY family. CC -!- SIMILARITY: Contains 1 HMG box DNA-binding domain. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB247629; BAE78533.1; -; Genomic_DNA. DR ProteinModelPortal; Q2MGT9; -. DR SMR; Q2MGT9; 51-130. DR HOVERGEN; HBG008712; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. DR GO; GO:0030238; P:male sex determination; IEA:InterPro. DR GO; GO:0007548; P:sex differentiation; IEA:UniProtKB-KW. DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. DR InterPro; IPR000910; HMG_HMG1/HMG2. DR InterPro; IPR009071; HMG_superfamily. DR InterPro; IPR017253; TF_Sry. DR Gene3D; G3DSA:1.10.30.10; HMG-box; 1. DR PANTHER; PTHR10270:SF48; PTHR10270:SF48; 1. DR Pfam; PF00505; HMG_box; 1. DR PIRSF; PIRSF037653; SRY; 1. DR SMART; SM00398; HMG; 1. DR SUPFAM; SSF47095; HMG-box; 1. DR PROSITE; PS50118; HMG_BOX_2; 1. PE 3: Inferred from homology; KW Activator; Differentiation; DNA-binding; Nucleus; KW Sexual differentiation; Transcription; Transcription regulation. SQ SEQUENCE 229 AA; 26771 MW; 541885529C4FB7A8 CRC64; MFRVLNDDVY STAKIQQQNP LAFGKASSLF TDNRSANDQC ETGENVRDSG QDHVKRPMNA FIVWSRERRR KVALENPKMQ NSEISKQLGY EWKRLTDAEK RPFFEEAQRL LAIHRDKYPG YKYRPRRKTK RHQKLLPADS SILRKQMHVE TLQPFTYRDG CAKTTCSRME SQLSLSQPVT ITNSFLQKEH HSSWTNLGHN RVTLATQISA DFPFYQSLQP GLSCSYFQY //