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Q2MD59

- Q2MD59_HUMAN

UniProt

Q2MD59 - Q2MD59_HUMAN

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Protein
Submitted name:

B-cell linker protein

Gene

BASH

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
B-cell linker proteinImported
Gene namesi
Name:BASHImported
Synonyms:BLNKImported, SLP65Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 10

Organism-specific databases

HGNCiHGNC:14211. BLNK.

PTM / Processingi

Proteomic databases

PRIDEiQ2MD59.

Expressioni

Gene expression databases

ExpressionAtlasiQ2MD59. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ2MD59.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063094.
HOGENOMiHOG000088646.
HOVERGENiHBG053147.
KOiK07371.
OrthoDBiEOG7WMCKM.

Family and domain databases

InterProiIPR000980. SH2.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q2MD59-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDKLNKITVP ASQKLRQLQK MVHDIKNNEG GIMNKIKKLK VKAPPSVPRR
60 70 80 90 100
DYASESPADE EEQWSDDFDS DYENPDEHSD SEMYVMPAEE NADDSYEPPP
110 120 130 140 150
VEQETRPVHP ALPFARGTAS GRNSGAWETK SPPPAAPSPL PRAGKKPTTP
160 170 180 190 200
LKTTPVASQQ NASSVCEEKP IPAERHRGSS HRQEAVQSPV FPPAQKQIHQ
210 220 230 240 250
KPIPLPRFTE GGNPTVDGPL PSFSSNSTIS EQEAGVLCKP WYAGACDRKS
260 270 280 290
AEEALHRSNK YFGSVAEIIR NHQHSPLVLI DSQNNTKDST RLKYAVKVS
Length:299
Mass (Da):32,998
Last modified:February 21, 2006 - v1
Checksum:i827C7D4AD2FB5048
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021037 Genomic DNA. No translation available.
KF455281 Genomic DNA. No translation available.
KF573679 Genomic DNA. No translation available.
AM180327 mRNA. Translation: CAJ55321.1.
RefSeqiNP_001245371.1. NM_001258442.1.
UniGeneiHs.665244.

Genome annotation databases

EnsembliENST00000427367; ENSP00000391924; ENSG00000095585.
GeneIDi29760.
KEGGihsa:29760.
UCSCiuc001klv.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021037 Genomic DNA. No translation available.
KF455281 Genomic DNA. No translation available.
KF573679 Genomic DNA. No translation available.
AM180327 mRNA. Translation: CAJ55321.1 .
RefSeqi NP_001245371.1. NM_001258442.1.
UniGenei Hs.665244.

3D structure databases

ProteinModelPortali Q2MD59.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q2MD59.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000427367 ; ENSP00000391924 ; ENSG00000095585 .
GeneIDi 29760.
KEGGi hsa:29760.
UCSCi uc001klv.4. human.

Organism-specific databases

CTDi 29760.
HGNCi HGNC:14211. BLNK.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00530000063094.
HOGENOMi HOG000088646.
HOVERGENi HBG053147.
KOi K07371.
OrthoDBi EOG7WMCKM.

Miscellaneous databases

GenomeRNAii 29760.
NextBioi 35507464.
52250.

Gene expression databases

ExpressionAtlasi Q2MD59. baseline and differential.

Family and domain databases

InterProi IPR000980. SH2.
[Graphical view ]
SUPFAMi SSF55550. SSF55550. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells."
    Sprangers M., Feldhahn N., Herzog S., Hansmann M.L., Reppel M., Hescheler J., Jumaa H., Siebert R., Muschen M.
    Oncogene 25:5056-5062(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ2MD59_HUMAN
AccessioniPrimary (citable) accession number: Q2MD59
Secondary accession number(s): F5GXS1
Entry historyi
Integrated into UniProtKB/TrEMBL: February 21, 2006
Last sequence update: February 21, 2006
Last modified: October 29, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3