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Protein
Submitted name:

B-cell linker protein

Gene

BASH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
B-cell linker proteinImported
Gene namesi
Name:BASHImported
Synonyms:BLNKImported, SLP65Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000172043.

Sequencei

Sequence statusi: Fragment.

Q2MD58-1 [UniParc]FASTAAdd to basket

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        10         20         30         40         50
MDKLNKITVP ASQKLRQLQK MVHDIKNNEG GIMNKIKKLK VKAPPSVPRR
60 70 80 90 100
DYASESPADE EEQWSDDFDS DYENPDEHSD SEMYVMPAEE NADDSYEPPP
110 120 130 140 150
VEQETRPVHP ALPFARGEYI DNRSSQRHSP PFSKTLPSKP SWPSEYFGSV
160 170 180
AEIIRNHQHS PLVLIDSQNN TKDSTRLKYA VKVS
Length:184
Mass (Da):21,019
Last modified:February 21, 2006 - v1
Checksum:i2173735C425B7060
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180328 mRNA. Translation: CAJ55322.1.
UniGeneiHs.665244.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180328 mRNA. Translation: CAJ55322.1.
UniGeneiHs.665244.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000172043.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells."
    Sprangers M., Feldhahn N., Herzog S., Hansmann M.L., Reppel M., Hescheler J., Jumaa H., Siebert R., Muschen M.
    Oncogene 25:5056-5062(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells."
    Sprangers M., Feldhahn N., Siebert R., Muschen M.
    Oncogene 25:5180-5186(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ2MD58_HUMAN
AccessioniPrimary (citable) accession number: Q2MD58
Entry historyi
Integrated into UniProtKB/TrEMBL: February 21, 2006
Last sequence update: February 21, 2006
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.