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Q2MD54

- Q2MD54_HUMAN

UniProt

Q2MD54 - Q2MD54_HUMAN

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Protein
Submitted name:

B-cell linker protein

Gene

BASH

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
B-cell linker proteinImported
Gene namesi
Name:BASHImported
Synonyms:BLNKImported, SLP65Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ2MD54.

Expressioni

Gene expression databases

BgeeiQ2MD54.
ExpressionAtlasiQ2MD54. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ2MD54.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG053147.
KOiK07371.

Family and domain databases

InterProiIPR000980. SH2.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q2MD54-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MDKLNKITVP ASQKLRQLQK MVHDIKNNEG GIMNKIKKLK VKAPPSVPRR
60 70 80 90 100
DYASESPADE EEQWSDDFDS DYENPDEHSD SEMYVMPAEE NADDSYEPPP
110 120 130 140 150
VEQETRPVHP ALPFARGEYI DNRSSQRHSP PFSKTLPSKP SWPSEKARLT
160 170 180 190 200
STLPALTALQ KPQVPPKPKG LLEDEADYVV PVEDNDENYI HPTESSSPPP
210 220 230 240 250
EKGRNSGAWE TKSPPPAAPS PLPRAGKKPT TPLKTTPVAS QQNASSVCEE
260 270 280 290 300
KPIPAERHRG SSHRQEAVQS PVFPPAQKQI HQKPIPLPRF TEGGNPTVDG
310 320 330 340 350
PLPSFSSNST ISEQEAGVLC KPWYAGACDR KSAEEALHRS NKYFGSVAEI
360 370 380
IRNHQHSPLV LIDSQNNTKD STRLKYAVKV S
Length:381
Mass (Da):42,213
Last modified:February 21, 2006 - v1
Checksum:iBCB444129B6FE88A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM180332 mRNA. Translation: CAJ55326.1.
RefSeqiNP_001245370.1. NM_001258441.1.
UniGeneiHs.665244.

Genome annotation databases

GeneIDi29760.
KEGGihsa:29760.
UCSCiuc001kma.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM180332 mRNA. Translation: CAJ55326.1 .
RefSeqi NP_001245370.1. NM_001258441.1.
UniGenei Hs.665244.

3D structure databases

ProteinModelPortali Q2MD54.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q2MD54.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 29760.
KEGGi hsa:29760.
UCSCi uc001kma.4. human.

Organism-specific databases

CTDi 29760.

Phylogenomic databases

HOVERGENi HBG053147.
KOi K07371.

Miscellaneous databases

GenomeRNAii 29760.
NextBioi 52250.

Gene expression databases

Bgeei Q2MD54.
ExpressionAtlasi Q2MD54. baseline and differential.

Family and domain databases

InterProi IPR000980. SH2.
[Graphical view ]
SUPFAMi SSF55550. SSF55550. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells."
    Sprangers M., Feldhahn N., Herzog S., Hansmann M.L., Reppel M., Hescheler J., Jumaa H., Siebert R., Muschen M.
    Oncogene 25:5056-5062(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells."
    Sprangers M., Feldhahn N., Siebert R., Muschen M.
    Oncogene 25:5180-5186(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ2MD54_HUMAN
AccessioniPrimary (citable) accession number: Q2MD54
Entry historyi
Integrated into UniProtKB/TrEMBL: February 21, 2006
Last sequence update: February 21, 2006
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.