Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

B-cell linker protein

Gene

BASH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
B-cell linker proteinImported
Gene namesi
Name:BASHImported
Synonyms:BLNKImported, SLP65Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ2MD54.

Expressioni

Gene expression databases

BgeeiQ2MD54.
ExpressionAtlasiQ2MD54. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ2MD54.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG053147.
KOiK07371.

Family and domain databases

InterProiIPR000980. SH2.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q2MD54-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDKLNKITVP ASQKLRQLQK MVHDIKNNEG GIMNKIKKLK VKAPPSVPRR
60 70 80 90 100
DYASESPADE EEQWSDDFDS DYENPDEHSD SEMYVMPAEE NADDSYEPPP
110 120 130 140 150
VEQETRPVHP ALPFARGEYI DNRSSQRHSP PFSKTLPSKP SWPSEKARLT
160 170 180 190 200
STLPALTALQ KPQVPPKPKG LLEDEADYVV PVEDNDENYI HPTESSSPPP
210 220 230 240 250
EKGRNSGAWE TKSPPPAAPS PLPRAGKKPT TPLKTTPVAS QQNASSVCEE
260 270 280 290 300
KPIPAERHRG SSHRQEAVQS PVFPPAQKQI HQKPIPLPRF TEGGNPTVDG
310 320 330 340 350
PLPSFSSNST ISEQEAGVLC KPWYAGACDR KSAEEALHRS NKYFGSVAEI
360 370 380
IRNHQHSPLV LIDSQNNTKD STRLKYAVKV S
Length:381
Mass (Da):42,213
Last modified:February 21, 2006 - v1
Checksum:iBCB444129B6FE88A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180332 mRNA. Translation: CAJ55326.1.
RefSeqiNP_001245370.1. NM_001258441.1.
UniGeneiHs.665244.

Genome annotation databases

GeneIDi29760.
KEGGihsa:29760.
UCSCiuc001kma.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180332 mRNA. Translation: CAJ55326.1.
RefSeqiNP_001245370.1. NM_001258441.1.
UniGeneiHs.665244.

3D structure databases

ProteinModelPortaliQ2MD54.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ2MD54.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi29760.
KEGGihsa:29760.
UCSCiuc001kma.4. human.

Organism-specific databases

CTDi29760.

Phylogenomic databases

HOVERGENiHBG053147.
KOiK07371.

Miscellaneous databases

GenomeRNAii29760.
NextBioi52250.

Gene expression databases

BgeeiQ2MD54.
ExpressionAtlasiQ2MD54. baseline and differential.

Family and domain databases

InterProiIPR000980. SH2.
[Graphical view]
SUPFAMiSSF55550. SSF55550. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells."
    Sprangers M., Feldhahn N., Herzog S., Hansmann M.L., Reppel M., Hescheler J., Jumaa H., Siebert R., Muschen M.
    Oncogene 25:5056-5062(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells."
    Sprangers M., Feldhahn N., Siebert R., Muschen M.
    Oncogene 25:5180-5186(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ2MD54_HUMAN
AccessioniPrimary (citable) accession number: Q2MD54
Entry historyi
Integrated into UniProtKB/TrEMBL: February 21, 2006
Last sequence update: February 21, 2006
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.