ID   Q2MD42_HUMAN            Unreviewed;        54 AA.
AC   Q2MD42;
DT   21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT   21-FEB-2006, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=B cell linker {ECO:0000313|Ensembl:ENSP00000512509.1};
DE   SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55338.1};
DE   Flags: Fragment;
GN   Name=BLNK {ECO:0000313|EMBL:CAJ55338.1,
GN   ECO:0000313|Ensembl:ENSP00000512509.1};
GN   Synonyms=BASH {ECO:0000313|EMBL:CAJ55338.1}, SLP65
GN   {ECO:0000313|EMBL:CAJ55338.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:CAJ55338.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000512509.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164054; DOI=10.1038/nature02462;
RA   Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA   Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA   Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA   Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA   Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N.,
RA   Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A.,
RA   Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C.,
RA   Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D.,
RA   Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C.,
RA   Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K.,
RA   Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A.,
RA   Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S.,
RA   McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S.,
RA   Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V.,
RA   Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A.,
RA   Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA   Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A.,
RA   Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P.,
RA   Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y.,
RA   Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D.,
RA   Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 10.";
RL   Nature 429:375-381(2004).
RN   [2] {ECO:0000313|EMBL:CAJ55338.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=16568084; DOI=10.1038/sj.onc.1209510;
RA   Sprangers M., Feldhahn N., Herzog S., Hansmann M.L., Reppel M.,
RA   Hescheler J., Jumaa H., Siebert R., Muschen M.;
RT   "The SRC family kinase LYN redirects B cell receptor signaling in human
RT   SLP65-deficient B cell lymphoma cells.";
RL   Oncogene 25:5056-5062(2006).
RN   [3] {ECO:0000313|EMBL:CAJ55338.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=16636677; DOI=10.1038/sj.onc.1209520;
RA   Sprangers M., Feldhahn N., Siebert R., Muschen M.;
RT   "SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-
RT   lymphoblastic leukemia and B-cell lymphoma cells.";
RL   Oncogene 25:5180-5186(2006).
RN   [4] {ECO:0000313|Ensembl:ENSP00000512509.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC021037; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455281; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF573679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AM180344; CAJ55338.1; -; mRNA.
DR   Ensembl; ENST00000696257.1; ENSP00000512509.1; ENSG00000095585.18.
DR   Ensembl; ENST00000696522.1; ENSP00000512686.1; ENSG00000095585.18.
DR   HGNC; HGNC:14211; BLNK.
DR   GeneTree; ENSGT00940000155715; -.
DR   ChiTaRS; BLNK; human.
DR   Proteomes; UP000005640; Chromosome 10.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|MaxQB:Q2MD42,
KW   ECO:0007829|PeptideAtlas:Q2MD42};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAJ55338.1"
SQ   SEQUENCE   54 AA;  6230 MW;  26123DB688DDC96D CRC64;
     MDKLNKITVP ASQKLRQLQK MVHDIKNNEG GIMNKIKKTA TMKIQMSTRT QRCT
//