Unreviewed,
UniProtKB/TrEMBL Q2M4J6 (Q2M4J6_MOUSE)
Last modified
June 16, 2009.
Version 30.
History...
Clusters with 100%,
90%,
50% identity |
Third-party data |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information
Names and origin
| Protein names | Submitted name: Interleukin 1 beta EMBL AAX90604.1 | ||||
| Gene names |
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| Organism | Mus musculus (Mouse) EMBL AAX90604.1 | ||||
| Taxonomic identifier | 10090 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus |
Protein attributes
| Sequence length | 269 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells By similarity. RuleBase RU003753V2 |
| Subunit structure | Monomer By similarity. RuleBase RU003753V2 |
| Sequence similarities | Belongs to the IL-1 family. RuleBase RU003752V1 |
Ontologies
Sequences
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References
| [1] | "Characterization of quantitative trait loci influencing growth and adiposity using congenic mouse strains." Farber C.R., Corva P.M., Medrano J.F. Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: CAST/EiJ EMBL AAX90604.1. Tissue: Spleen EMBL AAX90604.1. |
| [2] | Sycamore N. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. |
| [3] | "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. Stephenson L.D.Science 296:1661-1671(2002) [PubMed: 12040188] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL28238.1. |
| [4] | Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL28238.1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| AY902319 Genomic DNA. Translation: AAX90604.1. AL808143 Genomic DNA. Translation: CAM22719.1. CH466519 Genomic DNA. Translation: EDL28238.1. | |
| IPI | IPI00114067. |
| RefSeq | NP_032387.1. |
| UniGene | Mm.222830 |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| Ensembl | ENSMUSG00000027398. Mus musculus. [Contig view] |
| GeneID | 16176. |
| KEGG | mmu:16176. |
Organism-specific databases | |
| MGI | MGI:96543. Il1b. |
Phylogenomic databases | |
| HOVERGEN | Q2M4J6. |
| OMA | Q2M4J6. LYLSCVM. |
Gene expression databases | |
| ArrayExpress | Q2M4J6. |
| Bgee | Q2M4J6. |
Family and domain databases | |
| InterPro | IPR002348. IL1_HBGF. IPR003502. IL1_propep. IPR000975. Interleukin_1. IPR003294. InterleukinIL1AB. IPR003296. InterleukinIL1B. [Graphical view] |
| Pfam | PF00340. IL1. 1 hit. PF02394. IL1_propep. 1 hit. [Graphical view] |
| PRINTS | PR00262. IL1HBGF. PR00264. INTERLEUKIN1. PR01359. INTRLEUKIN1B. PR01357. INTRLEUKN1AB. |
| ProDom | PD002536. Interleukin_1. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| SMART | SM00125. IL1. 1 hit. [Graphical view] |
| PROSITE | PS00253. INTERLEUKIN_1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 289037. |
| SOURCE | Search... |
Entry information
| Entry name | Q2M4J6_MOUSE | ||||||||
| Accession | Primary (citable) accession number: Q2M4J6 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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