Q2M3A8 (MRAS1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative uncharacterized protein MRGPRG-AS1

Alternative name(s):
MRGPRG antisense RNA 1
MRGPRG antisense gene protein 1

Gene names

Name:	MRGPRG-AS1
Synonyms:	C11orf36
ORF Names:	HSD-40, HSD40

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	158 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Caution

Product of a dubious CDS prediction.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 158	158	Putative uncharacterized protein MRGPRG-AS1		PRO_0000251725
Natural variations
	Natural variant	6	1	E → A. Ref.1 Corresponds to variant rs11026002 [ dbSNP | Ensembl ].		VAR_027707
	Natural variant	135	1	S → F. Ref.1 Ref.2 Corresponds to variant rs11026004 [ dbSNP | Ensembl ].		VAR_027708
	Natural variant	142	1	G → V. Ref.1 Ref.2 Corresponds to variant rs12280457 [ dbSNP | Ensembl ].		VAR_027709
Experimental info
	Sequence conflict	3	1	L → S in BAC04158. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q2M3A8 [UniParc]. Last modified February 21, 2006. Version 1. Checksum: 5632F50B9DFEBF55	FASTA	158	16,456
	10 20 30 40 50 60 MDLASEITSA TQTSSLCSSG RGHAGYPAPG IVAHGFETHG TARVAQGHLL PPCLLPPPQM 70 80 90 100 110 120 PVLAALRDLS RRGSTSSSRS PSRPVSTSAS KPCLPASCLG ETWSISINLV GSSGHLQSPG 130 140 150 AQRDAQRETG CLGPSWLPHH QGRDEELSLS HSAQGEEF

References

[1]	"A new spermatogenesis-related gene." Yang C.B., Miao S.Y., Zhang X.D., Qiao Y., Liang G., Wang L.F. Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS ALA-6; PHE-135 AND VAL-142. Tissue: Testis.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS PHE-135 AND VAL-142. Tissue: Testis.
[3]	"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY422795 mRNA. Translation: AAR84193.1. AK093421 mRNA. Translation: BAC04158.1. AK097749 mRNA. Translation: BAC05159.1. AC109309 Genomic DNA. No translation available. BC104971 mRNA. No translation available. BC104973 mRNA. No translation available.
IPI	IPI00175215.
UniGene	Hs.151154.
3D structure databases
ModBase	Search...
Polymorphism databases
DMDM	115502126.
Proteomic databases
PRIDE	Q2M3A8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc001lxn.2. human.
Organism-specific databases
GeneCards	GC11P003240.
HGNC	HGNC:26691. MRGPRG-AS1.
neXtProt	NX_Q2M3A8.
GenAtlas	Search...
Phylogenomic databases
OMA	TWSISIN.
PhylomeDB	Q2M3A8.
Gene expression databases
ArrayExpress	Q2M3A8.
Bgee	Q2M3A8.
CleanEx	HS_C11orf36.
Genevestigator	Q2M3A8.
GermOnline	ENSG00000180359. Homo sapiens.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

MRAS1_HUMAN

Accession

Primary (citable) accession number: Q2M3A8
Secondary accession number(s): Q6TF48, Q8N7R8, Q8N9X7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 3, 2006
Last sequence update:	February 21, 2006
Last modified:	May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.