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Protein

Coiled-coil domain-containing protein 96

Gene

CCDC96

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 96
Gene namesi
Name:CCDC96
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000173013.5.
HGNCiHGNC:26900. CCDC96.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000173013.
PharmGKBiPA144596463.

Polymorphism and mutation databases

BioMutaiCCDC96.
DMDMi94707508.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002340961 – 555Coiled-coil domain-containing protein 96Add BLAST555

Proteomic databases

EPDiQ2M329.
MaxQBiQ2M329.
PaxDbiQ2M329.
PeptideAtlasiQ2M329.
PRIDEiQ2M329.

PTM databases

iPTMnetiQ2M329.
PhosphoSitePlusiQ2M329.

Expressioni

Gene expression databases

BgeeiENSG00000173013.
CleanExiHS_CCDC96.
GenevisibleiQ2M329. HS.

Organism-specific databases

HPAiHPA047546.

Interactioni

Protein-protein interaction databases

BioGridi129209. 1 interactor.
IntActiQ2M329. 1 interactor.
STRINGi9606.ENSP00000309285.

Structurei

3D structure databases

ProteinModelPortaliQ2M329.
SMRiQ2M329.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili305 – 441Sequence analysisAdd BLAST137
Coiled coili505 – 531Sequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi39 – 215Glu-richAdd BLAST177

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IFX0. Eukaryota.
ENOG410ZEWV. LUCA.
GeneTreeiENSGT00730000111440.
HOGENOMiHOG000111443.
HOVERGENiHBG081053.
InParanoidiQ2M329.
OMAiQAMGSCR.
OrthoDBiEOG091G0K7I.
PhylomeDBiQ2M329.
TreeFamiTF328830.

Family and domain databases

InterProiView protein in InterPro
IPR025254. DUF4201.
PfamiView protein in Pfam
PF13870. DUF4201. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2M329-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVSSEHTKD PGGEGGDGES LAARPSKIKA SSGPPTSPEP GELESEPEEE
60 70 80 90 100
EEEQAASQGG TAADEQAEAP KGLTAAEAAG EEGPGEPGRP AEPQPEPEEP
110 120 130 140 150
AEVGAEEPAQ PEPGAGPEEL EAEAGAEELE QAAEGKEVRF QASLPLTRID
160 170 180 190 200
EEEAAAAPEA ETERVEGEEE DKEETQRDGA ESKERDGEGR PAKSQEEGKR
210 220 230 240 250
LYGRDEFEDL EWSEEVQKLQ EQQLRSDLLD QYRSLLVERN RSQRYNLYLQ
260 270 280 290 300
HKIFEALRRK KGLEAAEVAD RGAEAEAPEK EQAYLRHLGM LEELKKQQAD
310 320 330 340 350
DLQWYHQELG QLKRQCQEKL TRVEKEWRRF QALKKQVVMQ AMGSCRMRGG
360 370 380 390 400
RQAALREVEQ IQALEDKKEK EMSAVRLENI QLKQSLVHFE TRMRTQEDLT
410 420 430 440 450
QGLLLIDFEQ LKIENQTFNE KIEERNEELL KLRSKVTNSV QVITHVKEKL
460 470 480 490 500
HFMDMENACK KTQLAEIEAQ AALGRDILTK TKQAREGLRT DNIRLNQKCG
510 520 530 540 550
LLGKDSLLRD LEEKVDKTEL LHRRLESLKR HHASLTLSCR GVRQKIREAK

AFLPS
Length:555
Mass (Da):62,711
Last modified:May 2, 2006 - v2
Checksum:i4C3E430F16287E97
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02616296E → K1 PublicationCorresponds to variant dbSNP:rs871134Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK075056 mRNA. Translation: BAC11373.1.
BC105055 mRNA. Translation: AAI05056.1.
BC112274 mRNA. Translation: AAI12275.1.
CCDSiCCDS3395.1.
RefSeqiNP_699207.1. NM_153376.2.
UniGeneiHs.656757.

Genome annotation databases

EnsembliENST00000310085; ENSP00000309285; ENSG00000173013.
GeneIDi257236.
KEGGihsa:257236.
UCSCiuc003gjv.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCCD96_HUMAN
AccessioniPrimary (citable) accession number: Q2M329
Secondary accession number(s): Q8N2I7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: May 2, 2006
Last modified: September 27, 2017
This is version 81 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations