Transient receptor potential 4 - Homo sapiens (Human)

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Unreviewed, UniProtKB/TrEMBL Q2M2U7 (Q2M2U7_HUMAN)

Last modified November 25, 2008. Version 22. History...

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Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
Transient receptor potential 4 EMBL AAI05642.1

Gene names

Name:

TRPC4 EMBL AAI05642.1

Organism

Homo sapiens (Human) EMBL AAI05642.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	977 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Membrane
Domain	ANK repeat RuleBase RU003321V2 Transmembrane RuleBase RU003378V0
Molecular function	Ionic channel RuleBase RU003378V0 Spearmint SPM005821 Receptor
Gene Ontology (GO)
Biological process	calcium ion transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	calcium channel activity Inferred from electronic annotation. Source: InterPro receptor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q2M2U7-1 [UniParc].

Last modified February 21, 2006. Version 1.
Checksum: 77E4D27C2121B60E
Show »

977

112,087

        10         20         30         40         50         60 
MAQFYYKRNV NAPYRDRIPL RIVRAESELS PSEKAYLNAV EKGDYASVKK SLEEAEIYFK 

        70         80         90        100        110        120 
ININCIDPLG RTALLIAIEN ENLELIELLL SFNVYVGDAL LHAIRKEVVG AVELLLNHKK 

       130        140        150        160        170        180 
PSGEKQVPPI LLDKQFSEFT PDITPIILAA HTNNYEIIKL LVQKGVSVPR PHEVRCNCVE 

       190        200        210        220        230        240 
CVSSSDVDSL RHSRSRLNIY KALASPSLIA LSSEDPFLTA FQLSWELQEL SKVENEFKSE 

       250        260        270        280        290        300 
YEELSRQCKQ FAKDLLDQTR SSRELEIILN YRDDNSLIEE QSGNDLARLK LAIKYRQKEF 

       310        320        330        340        350        360 
VAQPNCQQLL ASRWYDEFPG WRRRHWAVKM VTCFIIGLLF PVFSVCYLIA PKSPLGLFIR 

       370        380        390        400        410        420 
KPFIKFICHT ASYLTFLFLL LLASQHIDRS DLNRQGPPPT IVEWMILPWV LGFIWGEIKQ 

       430        440        450        460        470        480 
MWDGGLQDYI HDWWNLMDFV MNSLYLATIS LKIVAFVKYS ALNPRESWDM WHPTLVAEAL 

       490        500        510        520        530        540 
FAIANIFSSL RLISLFTANS HLGPLQISLG RMLLDILKFL FIYCLVLLAF ANGLNQLYFY 

       550        560        570        580        590        600 
YEETKGLTCK GIRCEKQNNA FSTLFETLQS LFWSIFGLIN LYVTNVKAQH EFTEFVGATM 

       610        620        630        640        650        660 
FGTYNVISLV VLLNMLIAMM NNSYQLIADH ADIEWKFART KLWMSYFEEG GTLPTPFNVI 

       670        680        690        700        710        720 
PSPKSLWYLI KWIWTHLCKK KMRRKPESFG TIGRRAADNL RRHHQYQEVM RNLVKRYVAA 

       730        740        750        760        770        780 
MIRDAKTEEG LTEENFKELK QDISSFRFEV LGLLRGSKLS TIQSANASKE SSNSADSDEK 

       790        800        810        820        830        840 
SDSEGNSKDK KKNFSLFDLT TLIHPRSAAI ASERHNISNG SALVVQEPPR EKQRKVNFVT 

       850        860        870        880        890        900 
DIKNFGLFHR RSKQNAAEQN ANQIFSVSEE VARQQAAGPL ERNIQLESRG LASRGDLSIP 

       910        920        930        940        950        960 
GLSEQCVLVD HRERNTDTLG LQVGKRVCPF KSEKVVVEDT VPIIPKEKHA KEEDSSVDYD 

       970 
LNLPDTVTHE DYVTTRL

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI05642.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
	BC105641 mRNA. Translation: AAI05642.1.
UniGene	Hs.262960
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000133107. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:12336. TRPC4.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q2M2U7.
Gene expression databases
ArrayExpress	Q2M2U7.
Family and domain databases
InterPro	IPR002110. ANK. IPR005821. Ion_trans. IPR001865. Ribosomal_S2. IPR002153. Trans_rcpt. IPR013555. TRP_2. IPR004729. TRP_channel. IPR005460. TRP_channel4. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
Pfam	PF00023. Ank. 2 hits. PF00520. Ion_trans. 1 hit. PF08344. TRP_2. 1 hit. [Graphical view]
PRINTS	PR01097. TRNSRECEPTRP. PR01645. TRPCHANNEL4.
SMART	SM00248. ANK. 2 hits. [Graphical view]
TIGRFAMs	TIGR00870. trp. 1 hit.
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 1 hit. PS00962. RIBOSOMAL_S2_1. 1 hit. Uncertain. [Graphical view]

Entry information

Entry name

Q2M2U7_HUMAN

Accession

Primary (citable) accession number: Q2M2U7

Entry history

Integrated into UniProtKB/TrEMBL:	February 21, 2006
Last sequence update:	February 21, 2006
Last modified:	November 25, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information