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Protein
Submitted name:

ATXN2 protein

Gene

ATXN2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
ATXN2 proteinImported
Gene namesi
Name:ATXN2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ2M2R5.
PRIDEiQ2M2R5.

Expressioni

Gene expression databases

BgeeiQ2M2R5.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000366843.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2375. Eukaryota.
COG5180. LUCA.
HOVERGENiHBG050623.

Family and domain databases

InterProiIPR009818. Ataxin-2_C.
IPR033093. ATXN2.
IPR010920. LSM_dom.
IPR009604. LsmAD_domain.
IPR025852. SM_dom_ATX.
[Graphical view]
PANTHERiPTHR12854:SF11. PTHR12854:SF11. 2 hits.
PfamiPF06741. LsmAD. 1 hit.
PF07145. PAM2. 1 hit.
PF14438. SM-ATX. 1 hit.
[Graphical view]
SMARTiSM01272. LsmAD. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q2M2R5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PRKQPSAPPA PHVSLPAPGP PHVLLPSDPS DFRGRNSNKG LPQSTISFDG
60 70 80 90 100
IYANMRMVHI LTSVVGSKCE VQVKNGGIYE GVFKTYSPKC DLVLDAAHEK
110 120 130 140 150
STESSSGPKR EEIMESILFK CSDFVVVQFK DMDSSYAKRD AFTDSAISAK
160 170 180 190 200
VNGEHKEKDL EPWDAGELTA NEELEALEND VSNGWDPNDM FRYNEENYGV
210 220 230 240 250
VSTYDSSLSS YTVPLERDNS EEFLKREARA NQLAEEIESS AQYKARVALE
260 270 280 290 300
NDDRSEEEKY TAVQRNSSER EGHSINTREN KYIPPGQRNR EVISWGSGRQ
310 320 330 340 350
NSPRMGQPGS GSMPSRSTSH TSDFNPNSGS DQRVVNGGVP WPSPCPSPSS
360 370 380 390 400
RPPSRYQSGP NSLPPRAATP TRPPSRPPSR PSRPPSHPSA HGSPAPVSTM
410 420 430 440 450
PKRMSSEGPP RMSPKAQRHP RNHRVSAGRG SISSGLEFVS HNPPSEAATP
460 470 480 490 500
PVARTSPSGG TWSSVVSGVP RLSPKTHRPR SPRQNSIGNT PSGPVLASPQ
510 520 530 540 550
AGIIPTEAVA MPIPAASPTP ASPASNRAVT PSSEAKDSRL QDQRQNSPAG
560 570 580 590 600
NKENIKPNET SPSFSKAENK GISPVVSEHR KQIDDLKKFK NDFRLQPSST
610 620 630 640 650
SESMDQLLNK NREGEKSRDL IKDKIEPSAK DSFIENSSSN CTSGSSKPNS
660 670 680 690 700
PSISPSILSN TEHKRGPEVT SQGVQTSSPA CKQEKDDKEE KKDAAEQVRK
710 720 730 740 750
STLNPNAKEF NPRSFSQPKP STTPTSPRPQ AQPSPSMVGH QQPTPVYTQP
760 770 780 790 800
VCFAPNMMYP VPVSPGVQPL YPIPMTPMPV NQAKTYRAVP NMPQQRQDQH
810 820 830 840 850
HQSAMMHPAS AAGPPIAATP PAYSTQYVAY SPQQFPNQPL VQHVPHYQSQ
860 870 880 890 900
HPHVYSPVIQ GNARMMAPPT HAQPGLVSSS ATQYGAHEQT HAMYACPKLP
910 920 930 940 950
YNKETSPSFY FAISTGSLAQ QYAHPNATLH PHTPHPQPSA TPTGQQQSQH
960 970 980 990 1000
GGSHPAPSPV QHHQHQAAQA LHLASPQQQS AIYHAGLAPT PPSMTPASNT
1010 1020 1030 1040 1050
QSPQNSFPAA QQTVFTIHPS HVQPAYTNPP HMAHVPQCAS EALARCGLEM
1060 1070 1080 1090 1100
RLSWIYLSEG YLAHVQSGMV PSHPTAHAPM MLMTTQPPGG PQAALAQSAL
1110 1120
QPIPVSTTAH FPYMTHPSVQ AHHQQQL
Length:1,127
Mass (Da):122,181
Last modified:February 21, 2006 - v1
Checksum:i0ADB2888EFD2C33E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111757 mRNA. Translation: AAI11758.1.
RefSeqiNP_001297050.1. NM_001310121.1.
UniGeneiHs.732512.
Hs.76253.

Genome annotation databases

GeneIDi6311.
KEGGihsa:6311.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111757 mRNA. Translation: AAI11758.1.
RefSeqiNP_001297050.1. NM_001310121.1.
UniGeneiHs.732512.
Hs.76253.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000366843.

Proteomic databases

PaxDbiQ2M2R5.
PRIDEiQ2M2R5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6311.
KEGGihsa:6311.

Organism-specific databases

CTDi6311.

Phylogenomic databases

eggNOGiKOG2375. Eukaryota.
COG5180. LUCA.
HOVERGENiHBG050623.

Miscellaneous databases

ChiTaRSiATXN2. human.
GenomeRNAii6311.

Gene expression databases

BgeeiQ2M2R5.

Family and domain databases

InterProiIPR009818. Ataxin-2_C.
IPR033093. ATXN2.
IPR010920. LSM_dom.
IPR009604. LsmAD_domain.
IPR025852. SM_dom_ATX.
[Graphical view]
PANTHERiPTHR12854:SF11. PTHR12854:SF11. 2 hits.
PfamiPF06741. LsmAD. 1 hit.
PF07145. PAM2. 1 hit.
PF14438. SM-ATX. 1 hit.
[Graphical view]
SMARTiSM01272. LsmAD. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiQ2M2R5_HUMAN
AccessioniPrimary (citable) accession number: Q2M2R5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 21, 2006
Last sequence update: February 21, 2006
Last modified: May 11, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.