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Q2M2N8

- Q2M2N8_MOUSE

UniProt

Q2M2N8 - Q2M2N8_MOUSE

Protein
Submitted name:

Gpr6 protein

Gene

Gpr6

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (21 Feb 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sphingosine-1-phosphate receptor activity Source: MGI

    GO - Biological processi

    1. positive regulation of cytosolic calcium ion concentration Source: MGI
    2. sphingosine-1-phosphate signaling pathway Source: GOC

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Gpr6 proteinImported
    Gene namesi
    Name:Gpr6Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:2155249. Gpr6.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    BgeeiQ2M2N8.
    GenevestigatoriQ2M2N8.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000057323.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2M2N8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.UniRule annotation

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    HOVERGENiHBG079561.
    InParanoidiQ2M2N8.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR001151. GPR6.
    IPR000723. GPR_3/6/12_orphan.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR00649. GPR6ORPHANR.
    PR00644. GPRORPHANR.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q2M2N8-1 [UniParc]FASTAAdd to Basket

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    AAALNESQVV AVAAEGAAAA ATAAGAPDTG EWGPPAASAA LGGGGGPNGS    50
    LELSSQLPAG PSGLLLSAVN PWDVLLCVSG TVIAGENALV VALIASTPAL 100
    RTPMFVLVGS LATADLLAGC GLILHFVFQY VVPSETVSLL MVGFLVASFA 150
    ASVSSLLAIT VDRYLSLYNA LTYYSRRTLL GVHLLLAATW TVSLGLGLLP 200
    VLGWNCLADR TSCSVVRPLT RSHVALLSTS FFVVFGIMLH LYVRICQVVW 250
    RHAHQIALQQ HCLAPPHLAA TRKGVGTLAV VLGTFGASWL PFAIYCVVGS 300
    QEDPAIYTYA TLLPATYNSM INPIIYAFRN QEIQRALWLL FCGCFQSKVP 350
    FRSRSPSEV 359
    Length:359
    Mass (Da):37,682
    Last modified:February 21, 2006 - v1
    Checksum:iE19019FF84C7A838
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC111861 mRNA. Translation: AAI11862.1.
    UniGeneiMm.290693.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC111861 mRNA. Translation: AAI11862.1 .
    UniGenei Mm.290693.

    3D structure databases

    ProteinModelPortali Q2M2N8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000057323.

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:2155249. Gpr6.

    Phylogenomic databases

    HOVERGENi HBG079561.
    InParanoidi Q2M2N8.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Bgeei Q2M2N8.
    Genevestigatori Q2M2N8.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR001151. GPR6.
    IPR000723. GPR_3/6/12_orphan.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR00649. GPR6ORPHANR.
    PR00644. GPRORPHANR.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: PCR rescued clonesImported.

    Entry informationi

    Entry nameiQ2M2N8_MOUSE
    AccessioniPrimary (citable) accession number: Q2M2N8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 21, 2006
    Last sequence update: February 21, 2006
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)