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Protein
Submitted name:

BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa

Gene

BTAF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDaImported
Submitted name:
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae), isoform CRA_aImported
Gene namesi
Name:BTAF1Imported
ORF Names:hCG_19287Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25437.

Expressioni

Gene expression databases

BgeeiENSG00000095564.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PIH1D3Q9NQM43EBI-10239305,EBI-10239299

Protein-protein interaction databases

STRINGi9606.ENSP00000265990.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1278 – 1453Helicase ATP-bindingInterPro annotationAdd BLAST176
Domaini1636 – 1790Helicase C-terminalInterPro annotationAdd BLAST155

Phylogenomic databases

eggNOGiKOG0387. Eukaryota.
ENOG410XP4Z. LUCA.
KOiK15192.
OMAiREEDMVD.

Family and domain databases

Gene3Di1.25.10.10. 5 hits.
3.40.50.300. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR022707. DUF3535.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000330. SNF2_N.
[Graphical view]
PfamiPF12054. DUF3535. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00176. SNF2_N. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 5 hits.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2M1V9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVSRLDRLF ILLDTGTTPV TRKAAAQQLG EVVKLHPHEL NNLLSKVLIY
60 70 80 90 100
LRSANWDTRI AAGQAVEAIV KNVPEWNPVP RTRQEPTSES SMEDSPTTER
110 120 130 140 150
LNFDRFDICR LLQHGASLLG SAGAEFEVQD EKSGEVDPKE RIARQRKLLQ
160 170 180 190 200
KKLGLNMGEA IGMSTEELFN DEDLDYTPTS ASFVNKQPTL QAAELIDSEF
210 220 230 240 250
RAGMSNRQKN KAKRMAKLFA KQRSRDAVET NEKSNDSTDG EPEEKRRKIA
260 270 280 290 300
NVVINQSAND SKVLIDNIPD SSSLIEETNE WPLESFCEEL CNDLFNPSWE
310 320 330 340 350
VRHGAGTGLR EILKAHGKSG GKMGDSTLEE MIQQHQEWLE DLVIRLLCVF
360 370 380 390 400
ALDRFGDFVS DEVVAPVRET CAQTLGVVLK HMNETGVHKT VDVLLKLLTQ
410 420 430 440 450
EQWEVRHGGL LGIKYALAVR QDVINTLLPK VLTRIIEGLQ DLDDDVRAVA
460 470 480 490 500
AASLVPVVES LVYLQTQKVP FIINTLWDAL LELDDLTAST NSIMTLLSSL
510 520 530 540 550
LTYPQVQQCS IQQSLTVLVP RVWPFLHHTI SSVRRAALET LFTLLSTQDQ
560 570 580 590 600
NSSSWLIPIL PDMLRHIFQF CVLESSQEIL DLIHKVWMEL LSKASVQYVV
610 620 630 640 650
AAACPWMGAW LCLMMQPSHL PIDLNMLLEV KARAKEKTGG KVRQGQSQNK
660 670 680 690 700
EVLQEYIAGA DTIMEDPATR DFVVMRARMM AAKLLGALCC CICDPGVNVV
710 720 730 740 750
TQEIKPAESL GQLLLFHLNS KSALQRISVA LVICEWAALQ KECKAVTLAV
760 770 780 790 800
QPRLLDILSE HLYYDEIAVP FTRMQNECKQ LISSLADVHI EVGNRVNNNV
810 820 830 840 850
LTIDQASDLV TTVFNEATSS FDLNPQVLQQ LDSKRQQVQM TVTETNQEWQ
860 870 880 890 900
VLQLRVHTFA ACAVVSLQQL PEKLNPIIKP LMETIKKEEN TLVQNYAAQC
910 920 930 940 950
IAKLLQQCTT RTPCPNSKII KNLCSSLCVD PYLTPCVTCP VPTQSGQENS
960 970 980 990 1000
KGSTSEKDGM HHTVTKHRGI ITLYRHQKAA FAITSRRGPT PKAVKAQIAD
1010 1020 1030 1040 1050
LPAGSSGNIL VELDEAQKPY LVQRRGAEFA LTTIVKHFGG EMAVKLPHLW
1060 1070 1080 1090 1100
DAMVGPLRNT IDINNFDGKS LLDKGDSPAQ ELVNSLQVFE TAAASMDSEL
1110 1120 1130 1140 1150
HPLLVQHLPH LYMCLQYPST AVRHMAARCV GVMSKIATME TMNIFLEKVL
1160 1170 1180 1190 1200
PWLGAIDDSV KQEGAIEALA CVMEQLDVGI VPYIVLLVVP VLGRMSDQTD
1210 1220 1230 1240 1250
SVRFMATQCF ATLIRLMPLE AGIPDPPNMS AELIQLKAKE RHFLEQLLDG
1260 1270 1280 1290 1300
KKLENYKIPV PINAELRKYQ QDGVNWLAFL NKYKLHGILC DDMGLGKTLQ
1310 1320 1330 1340 1350
SICILAGDHC HRAQEYARSK LAECMPLPSL VVCPPTLTGH WVDEVGKFCS
1360 1370 1380 1390 1400
REYLNPLHYT GPPTERIRLQ HQVKRHNLIV ASYDVVRNDI DFFRNIKFNY
1410 1420 1430 1440 1450
CILDEGHVIK NGKTKLSKAV KQLTANYRII LSGTPIQNNV LELWSLFDFL
1460 1470 1480 1490 1500
MPGFLGTERQ FAARYGKPIL ASRDARSSSR EQEAGVLAMD ALHRQVLPFL
1510 1520 1530 1540 1550
LRRMKEDVLQ DLPPKIIQDY YCTLSPLQVQ LYEDFAKSRA KCDVDETVSS
1560 1570 1580 1590 1600
ATLSEETEKP KLKATGHVFQ ALQYLRKLCN HPALVLTPQH PEFKTTAEKL
1610 1620 1630 1640 1650
AVQNSSLHDI QHAPKLSALK QLLLDCGLGN GSTSESGTES VVAQHRILIF
1660 1670 1680 1690 1700
CQLKSMLDIV EHDLLKPHLP SVTYLRLDGS IPPGQRHSIV SRFNNDPSID
1710 1720 1730 1740 1750
VLLLTTHVGG LGLNLTGADT VVFVEHDWNP MRDLQAMDRA HRIGQKRVVN
1760 1770 1780 1790 1800
VYRLITRGTL EEKIMGLQKF KMNIANTVIS QENSSLQSMG TDQLLDLFTL
1810 1820 1830 1840
DKDGKAEKAD TSTSGKASMK SILENLSDLW DQEQYDSEYS LENFMHSLK
Length:1,849
Mass (Da):206,887
Last modified:April 14, 2009 - v1
Checksum:iFE3675B75A44F113
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112201 mRNA. Translation: AAI12202.1.
CH471066 Genomic DNA. Translation: EAW50102.1.
CH471066 Genomic DNA. Translation: EAW50103.1.
RefSeqiNP_003963.1. NM_003972.2.
UniGeneiHs.500526.

Genome annotation databases

GeneIDi9044.
KEGGihsa:9044.
UCSCiuc001khr.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112201 mRNA. Translation: AAI12202.1.
CH471066 Genomic DNA. Translation: EAW50102.1.
CH471066 Genomic DNA. Translation: EAW50103.1.
RefSeqiNP_003963.1. NM_003972.2.
UniGeneiHs.500526.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000265990.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9044.
KEGGihsa:9044.
UCSCiuc001khr.4. human.

Organism-specific databases

CTDi9044.
PharmGKBiPA25437.

Phylogenomic databases

eggNOGiKOG0387. Eukaryota.
ENOG410XP4Z. LUCA.
KOiK15192.
OMAiREEDMVD.

Miscellaneous databases

ChiTaRSiBTAF1. human.
GenomeRNAii9044.

Gene expression databases

BgeeiENSG00000095564.

Family and domain databases

Gene3Di1.25.10.10. 5 hits.
3.40.50.300. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR022707. DUF3535.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000330. SNF2_N.
[Graphical view]
PfamiPF12054. DUF3535. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00176. SNF2_N. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 5 hits.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ2M1V9_HUMAN
AccessioniPrimary (citable) accession number: Q2M1V9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 14, 2009
Last sequence update: April 14, 2009
Last modified: November 30, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.