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Protein

Zinc transporter ZIP13

Gene

Slc39a13

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Acts as a zinc-influx transporter.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Transport, Zinc transport

Keywords - Ligandi

Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc transporter ZIP13
Alternative name(s):
Solute carrier family 39 member 13
Zrt- and Irt-like protein 13
Short name:
ZIP-13
Gene namesi
Name:Slc39a13
Synonyms:Zip13
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1304695. Slc39a13.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 6LumenalSequence analysis6
Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Topological domaini28 – 68CytoplasmicSequence analysisAdd BLAST41
Transmembranei69 – 89HelicalSequence analysisAdd BLAST21
Topological domaini90 – 108LumenalSequence analysisAdd BLAST19
Transmembranei109 – 129HelicalSequence analysisAdd BLAST21
Topological domaini130 – 150CytoplasmicSequence analysisAdd BLAST21
Transmembranei151 – 171HelicalSequence analysisAdd BLAST21
Topological domaini172 – 233LumenalSequence analysisAdd BLAST62
Transmembranei234 – 254HelicalSequence analysisAdd BLAST21
Topological domaini255 – 276CytoplasmicSequence analysisAdd BLAST22
Transmembranei277 – 297HelicalSequence analysisAdd BLAST21
Topological domaini298 – 307LumenalSequence analysis10
Transmembranei308 – 328HelicalSequence analysisAdd BLAST21
Topological domaini329 – 340CytoplasmicSequence analysisAdd BLAST12
Transmembranei341 – 361HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003123121 – 361Zinc transporter ZIP13Add BLAST361

Proteomic databases

PaxDbiQ2M1K6.
PRIDEiQ2M1K6.

Expressioni

Gene expression databases

BgeeiENSRNOG00000011981.
GenevisibleiQ2M1K6. RN.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000016191.

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi255 – 260XEXPHE-motif6

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi42 – 45Poly-Ala4

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2694. Eukaryota.
COG0428. LUCA.
GeneTreeiENSGT00760000119115.
HOGENOMiHOG000185308.
HOVERGENiHBG001037.
InParanoidiQ2M1K6.
KOiK14719.
OMAiEEDDPWH.
OrthoDBiEOG091G0GD1.
PhylomeDBiQ2M1K6.
TreeFamiTF318470.

Family and domain databases

InterProiIPR003689. ZIP.
[Graphical view]
PfamiPF02535. Zip. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2M1K6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGCPCPGCG MAGQRLLFLT VLALELLERA GGSQPALRSL GAAAACRLDS
60 70 80 90 100
KESESWGALL SGERLDTWIC SLLGSLMVGL SGVFPLLVIP LEMGTMLQSE
110 120 130 140 150
AGAWRLKQLL SFALGGLLGN VFLHLLPEAW AYTCNISPGV EGQSLQRQQQ
160 170 180 190 200
LGLWVIAGFL TFLALEKMFL NCKEEDPSQA PSKDPTAAAL NGGHCLAQPA
210 220 230 240 250
AEPGLRAVVR NLKVSGYLNL LANTIDNFTH GLAVAASFLV SKKIGLLTTM
260 270 280 290 300
AILLHEIPHE VGDFAILLRA GFDRWTAAKL QFSTALGGLL GACFAICTQS
310 320 330 340 350
PKGVEETVVW TLPFTSGGFL YVALVNVLPD LLEEDDPWHL NPPLPTGTPC
360
SRCCCSAPVS W
Length:361
Mass (Da):38,398
Last modified:February 21, 2006 - v1
Checksum:i8AC365D6F3A2BCB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112321 mRNA. Translation: AAI12322.1.
RefSeqiNP_001034285.1. NM_001039196.1.
UniGeneiRn.17295.

Genome annotation databases

EnsembliENSRNOT00000016191; ENSRNOP00000016191; ENSRNOG00000011981.
GeneIDi295928.
KEGGirno:295928.
UCSCiRGD:1304695. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112321 mRNA. Translation: AAI12322.1.
RefSeqiNP_001034285.1. NM_001039196.1.
UniGeneiRn.17295.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000016191.

Proteomic databases

PaxDbiQ2M1K6.
PRIDEiQ2M1K6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000016191; ENSRNOP00000016191; ENSRNOG00000011981.
GeneIDi295928.
KEGGirno:295928.
UCSCiRGD:1304695. rat.

Organism-specific databases

CTDi91252.
RGDi1304695. Slc39a13.

Phylogenomic databases

eggNOGiKOG2694. Eukaryota.
COG0428. LUCA.
GeneTreeiENSGT00760000119115.
HOGENOMiHOG000185308.
HOVERGENiHBG001037.
InParanoidiQ2M1K6.
KOiK14719.
OMAiEEDDPWH.
OrthoDBiEOG091G0GD1.
PhylomeDBiQ2M1K6.
TreeFamiTF318470.

Miscellaneous databases

PROiQ2M1K6.

Gene expression databases

BgeeiENSRNOG00000011981.
GenevisibleiQ2M1K6. RN.

Family and domain databases

InterProiIPR003689. ZIP.
[Graphical view]
PfamiPF02535. Zip. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS39AD_RAT
AccessioniPrimary (citable) accession number: Q2M1K6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: February 21, 2006
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.