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Protein

Zinc transporter ZIP13

Gene

Slc39a13

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Acts as a zinc-influx transporter.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Transport, Zinc transport

Keywords - Ligandi

Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc transporter ZIP13
Alternative name(s):
Solute carrier family 39 member 13
Zrt- and Irt-like protein 13
Short name:
ZIP-13
Gene namesi
Name:Slc39a13
Synonyms:Zip13
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1304695. Slc39a13.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 66LumenalSequence analysis
Transmembranei7 – 2721HelicalSequence analysisAdd
BLAST
Topological domaini28 – 6841CytoplasmicSequence analysisAdd
BLAST
Transmembranei69 – 8921HelicalSequence analysisAdd
BLAST
Topological domaini90 – 10819LumenalSequence analysisAdd
BLAST
Transmembranei109 – 12921HelicalSequence analysisAdd
BLAST
Topological domaini130 – 15021CytoplasmicSequence analysisAdd
BLAST
Transmembranei151 – 17121HelicalSequence analysisAdd
BLAST
Topological domaini172 – 23362LumenalSequence analysisAdd
BLAST
Transmembranei234 – 25421HelicalSequence analysisAdd
BLAST
Topological domaini255 – 27622CytoplasmicSequence analysisAdd
BLAST
Transmembranei277 – 29721HelicalSequence analysisAdd
BLAST
Topological domaini298 – 30710LumenalSequence analysis
Transmembranei308 – 32821HelicalSequence analysisAdd
BLAST
Topological domaini329 – 34012CytoplasmicSequence analysisAdd
BLAST
Transmembranei341 – 36121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361Zinc transporter ZIP13PRO_0000312312Add
BLAST

Proteomic databases

PaxDbiQ2M1K6.
PRIDEiQ2M1K6.

Expressioni

Gene expression databases

GenevisibleiQ2M1K6. RN.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000016191.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi255 – 2606XEXPHE-motif

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi42 – 454Poly-Ala

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2694. Eukaryota.
COG0428. LUCA.
GeneTreeiENSGT00760000119115.
HOGENOMiHOG000185308.
HOVERGENiHBG001037.
InParanoidiQ2M1K6.
KOiK14719.
OMAiEEDDPWH.
OrthoDBiEOG73NG48.
PhylomeDBiQ2M1K6.
TreeFamiTF318470.

Family and domain databases

InterProiIPR003689. ZIP.
[Graphical view]
PfamiPF02535. Zip. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2M1K6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGCPCPGCG MAGQRLLFLT VLALELLERA GGSQPALRSL GAAAACRLDS
60 70 80 90 100
KESESWGALL SGERLDTWIC SLLGSLMVGL SGVFPLLVIP LEMGTMLQSE
110 120 130 140 150
AGAWRLKQLL SFALGGLLGN VFLHLLPEAW AYTCNISPGV EGQSLQRQQQ
160 170 180 190 200
LGLWVIAGFL TFLALEKMFL NCKEEDPSQA PSKDPTAAAL NGGHCLAQPA
210 220 230 240 250
AEPGLRAVVR NLKVSGYLNL LANTIDNFTH GLAVAASFLV SKKIGLLTTM
260 270 280 290 300
AILLHEIPHE VGDFAILLRA GFDRWTAAKL QFSTALGGLL GACFAICTQS
310 320 330 340 350
PKGVEETVVW TLPFTSGGFL YVALVNVLPD LLEEDDPWHL NPPLPTGTPC
360
SRCCCSAPVS W
Length:361
Mass (Da):38,398
Last modified:February 21, 2006 - v1
Checksum:i8AC365D6F3A2BCB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112321 mRNA. Translation: AAI12322.1.
RefSeqiNP_001034285.1. NM_001039196.1.
UniGeneiRn.17295.

Genome annotation databases

EnsembliENSRNOT00000016191; ENSRNOP00000016191; ENSRNOG00000011981.
GeneIDi295928.
KEGGirno:295928.
UCSCiRGD:1304695. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112321 mRNA. Translation: AAI12322.1.
RefSeqiNP_001034285.1. NM_001039196.1.
UniGeneiRn.17295.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000016191.

Proteomic databases

PaxDbiQ2M1K6.
PRIDEiQ2M1K6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000016191; ENSRNOP00000016191; ENSRNOG00000011981.
GeneIDi295928.
KEGGirno:295928.
UCSCiRGD:1304695. rat.

Organism-specific databases

CTDi91252.
RGDi1304695. Slc39a13.

Phylogenomic databases

eggNOGiKOG2694. Eukaryota.
COG0428. LUCA.
GeneTreeiENSGT00760000119115.
HOGENOMiHOG000185308.
HOVERGENiHBG001037.
InParanoidiQ2M1K6.
KOiK14719.
OMAiEEDDPWH.
OrthoDBiEOG73NG48.
PhylomeDBiQ2M1K6.
TreeFamiTF318470.

Miscellaneous databases

PROiQ2M1K6.

Gene expression databases

GenevisibleiQ2M1K6. RN.

Family and domain databases

InterProiIPR003689. ZIP.
[Graphical view]
PfamiPF02535. Zip. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Prostate.

Entry informationi

Entry nameiS39AD_RAT
AccessioniPrimary (citable) accession number: Q2M1K6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: February 21, 2006
Last modified: June 8, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.