Q2M096 (Q2M096_DROPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aldose 1-epimerase PIRNR PIRNR005096
EC=5.1.3.3 PIRNR PIRNR005096

Alternative name(s):
Galactose mutarotase PIRNR PIRNR005096

Gene names

Name:	Dpse\GA16909 EMBL EAL31039.2
ORF Names:	Dpse_GA16909 EMBL EAL31039.2, GA16909 FlyBase FBgn0076923

Organism

Drosophila pseudoobscura pseudoobscura (Fruit fly) [Reference proteome] EMBL EAL31039.2

Taxonomic identifier

46245 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › obscura group › pseudoobscura subgroup › Drosophila pseudoobscura

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity. PIRNR PIRNR005096
Catalytic activity	Alpha-D-glucose = beta-D-glucose. PIRNR PIRNR005096
Pathway	Carbohydrate metabolism; hexose metabolism. PIRNR PIRNR005096
Sequence similarities	Belongs to the aldose epimerase family. PIRNR PIRNR005096

Ontologies

Keywords
Biological process	Carbohydrate metabolism PIRNR PIRNR005096
Molecular function	Isomerase PIRNR PIRNR005096 EMBL EAL31039.2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	hexose metabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	aldose 1-epimerase activity Inferred from electronic annotation. Source: EC carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2M096 [UniParc]. Last modified October 14, 2008. Version 2. Checksum: 8BCE49F245FFCAA9	FASTA	376	41,906
	10 20 30 40 50 60 MPITLEEEIF GLAVNPFTKA PEMVRRYTLT NSNRMSISVI QLGAIIQSVR MPDAYEKVDD 70 80 90 100 110 120 ICLGFDDIAS YVATKGAYIG GTLGRVANRV ANGEYVVGET KVELTKNFQN KYQLHGGLVG 130 140 150 160 170 180 FDSVIWEVVQ KTEDGIVFRH VSAHGHEGYP GTLTCLITYW LDNQNRIGVQ FEATTDRKTV 190 200 210 220 230 240 VNISNHAYFN LAGHSAGPKG LAEHTVEIAA SKIVETDDQQ IPTGQLVDVD DTVFDLRLPV 250 260 270 280 290 300 LLGDRLMQFG GSLIDGYDNC FVVNGGSTQP GLSMIAKLVH PPSCRVMEVW TNQPGLQFYT 310 320 330 340 350 360 ANNLPNEKSG EFPMIGKDCT HYVKHGSFCV ETEKFPDSMN HPEFPSIFLE PGEKYQHEVM 370 YWFKVEESWK CCCNNK

References

[1]

"Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution." Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A. Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MV2-25 / Tucson 14011-0121.94.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH379069 Genomic DNA. Translation: EAL31039.2.
RefSeq	XP_001353527.2. XM_001353491.2.
3D structure databases
ProteinModelPortal	Q2M096.
ModBase	Search...
Protein-protein interaction databases
STRING	7237.FBpp0274468.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0276030; FBpp0274468; FBgn0076923.
GeneID	4812826.
KEGG	dpo:Dpse_GA16909.
Organism-specific databases
FlyBase	FBgn0076923. Dpse\GA16909.
Phylogenomic databases
InParanoid	Q2M096.
KO	K01785.
OrthoDB	EOG4DNCKX.
Enzyme and pathway databases
UniPathway	UPA00242.
Family and domain databases
Gene3D	2.70.98.10. 1 hit.
InterPro	IPR015443. Aldose_1-epimerase. IPR008183. Aldose_1/G6P_1-epimerase. IPR011013. Gal_mutarotase_SF_dom. IPR014718. Glyco_hydro-type_carb-bd_sub. [Graphical view]
PANTHER	PTHR10091. PTHR10091. 1 hit.
Pfam	PF01263. Aldose_epim. 1 hit. [Graphical view]
PIRSF	PIRSF005096. GALM. 1 hit.
SUPFAM	SSF74650. Gal_mut_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2M096_DROPS

Accession

Primary (citable) accession number: Q2M096

Entry history

Integrated into UniProtKB/TrEMBL:	February 21, 2006
Last sequence update:	October 14, 2008
Last modified:	May 29, 2013
This is version 45 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)