Q2LZW7 (Q2LZW7_DROPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Gad1 EMBL EAL31170.1
EC=4.1.1.- EMBL EAL31170.1

Gene names

Name:	Gad1 FlyBase FBgn0023295
Synonyms:	Dpse\Gad1 EMBL EAL31170.1
ORF Names:	Dpse_GA13411 EMBL EAL31170.1, GA13411 FlyBase FBgn0023295

Organism

Drosophila pseudoobscura pseudoobscura (Fruit fly) [Reference proteome] EMBL EAL31170.1

Taxonomic identifier

46245 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › obscura group › pseudoobscura subgroup › Drosophila pseudoobscura

Protein attributes

Sequence length	510 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382 EMBL EAL31170.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	carboxylic acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	carboxy-lyase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2LZW7 [UniParc]. Last modified February 21, 2006. Version 1. Checksum: 112C34A9630AA775	FASTA	510	57,756
	10 20 30 40 50 60 MSLNPNGYKL SERTGKLTAY DLMPTTVSAG PETQEFLLKV VDVLLDFVKA TNDRNEKVLD 70 80 90 100 110 120 FHHPEDLKRL LDLEVPDRAL PLQQLIEDCA TTLKYQVKTG HPHFFNQLSN GLDLISMAGE 130 140 150 160 170 180 WLTATANTNM FTYEIAPVFI LMETVVLTKM REIIGWSGGD SILAPGGSIS NLYAFLAARH 190 200 210 220 230 240 KMFPNYKEHG SRGLPGNLAM FTSDQCHYSI KSCAAVCGLG TDHCIVVPSD EHGKMITSEL 250 260 270 280 290 300 ERLILERKAK GDIPFFVNAT AGTTVLGAFD DINTIADICE KYNCWMHIDA AWGGGLLMSR 310 320 330 340 350 360 KHRHPRFTGV ERADSVTWNP HKLMGALLQC STIHFKEDGL LISCNQMSAE YLFMTDKHYD 370 380 390 400 410 420 ISYDTGDKVI QCGRHNDIFK LWLQWRAKGT EGFEQQQDRL MELVQYQLKR IRAQSDRFHL 430 440 450 460 470 480 ILEPECVNVS FWYVPKRLRG VPHDARKETE LGKICPIIKG RMMQKGSLMV GYQPDDRRPN 490 500 510 FFRSIISSAA VNEADVDFML DEIHRLGDDL

References

[1]

"Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution." Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A. Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MV2-25 / Tucson 14011-0121.94.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH379069 Genomic DNA. Translation: EAL31170.1.
RefSeq	XP_001353656.1. XM_001353620.2.
3D structure databases
ProteinModelPortal	Q2LZW7.
SMR	Q2LZW7. Positions 15-509.
ModBase	Search...
Protein-protein interaction databases
STRING	7237.FBpp0275205.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0276767; FBpp0275205; FBgn0023295.
GeneID	4813307.
KEGG	dpo:Dpse_GA13411.
Organism-specific databases
FlyBase	FBgn0023295. Dpse\Gad1.
Phylogenomic databases
InParanoid	Q2LZW7.
KO	K01580.
OMA	ISMAGEW.
Family and domain databases
Gene3D	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
InterPro	IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. IPR021115. Pyridoxal-P_BS. [Graphical view]
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00392. DDC_GAD_HDC_YDC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2LZW7_DROPS

Accession

Primary (citable) accession number: Q2LZW7

Entry history

Integrated into UniProtKB/TrEMBL:	February 21, 2006
Last sequence update:	February 21, 2006
Last modified:	May 29, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)