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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Syntrophus aciditrophicus (strain SB)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei38NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciSACI56780:G1G5X-2543-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:SYNAS_26720
ORF Names:SYN_01783
OrganismiSyntrophus aciditrophicus (strain SB)
Taxonomic identifieri56780 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophaceaeSyntrophus
Proteomesi
  • UP000001933 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000847041 – 312tRNA pseudouridine synthase BAdd BLAST312

Interactioni

Protein-protein interaction databases

STRINGi56780.SYN_01783

Structurei

3D structure databases

ProteinModelPortaliQ2LWU1
SMRiQ2LWU1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231225
KOiK03177
OMAiHVMSITA
OrthoDBiPOG091H02G9

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q2LWU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGILILDKS PGKTSQKVVQ EVKRILGVRK AGHAGTLDPL ATGVLPLCLN
60 70 80 90 100
EATKLVQFLS LDDKEYRATM LLGVTTETMD IEGRITDRRE PEVDEVRIRE
110 120 130 140 150
ALQFFTGPIS QEPPRYSAVK FKGRPLYSWA RKGVDIALPP RTVQVYSSIL
160 170 180 190 200
EEIALPYVTF RVACSKGTYI RTLCADLGER LGCGACMSVL RRLRCGCFTL
210 220 230 240 250
ETAVSLEDIA DGKGRETLLS RVIPLSDGLR NVAAIEISEE LSGRIRDGFQ
260 270 280 290 300
PDGSTLREYH IPSLADGDMV KFLTSSGGLV AVARFLYASD QLAVSDMGQP
310
AVRILRVFHD RA
Length:312
Mass (Da):34,305
Last modified:February 21, 2006 - v1
Checksum:i11DDAA1854061950
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000252 Genomic DNA Translation: ABC78551.1
RefSeqiWP_011418570.1, NC_007759.1

Genome annotation databases

EnsemblBacteriaiABC78551; ABC78551; SYN_01783
KEGGisat:SYN_01783

Similar proteinsi

Entry informationi

Entry nameiTRUB_SYNAS
AccessioniPrimary (citable) accession number: Q2LWU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 21, 2006
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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