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Q2LWU1

- TRUB_SYNAS

UniProt

Q2LWU1 - TRUB_SYNAS

Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Syntrophus aciditrophicus (strain SB)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (21 Feb 2006)
      Previous versions | rss
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    • Comment

    Functioni

    Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

    Catalytic activityi

    tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei38 – 381NucleophileUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    tRNA processing

    Enzyme and pathway databases

    BioCyciSACI56780:GHXT-2722-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(55) synthaseUniRule annotation
    Short name:
    Psi55 synthaseUniRule annotation
    tRNA pseudouridylate synthaseUniRule annotation
    tRNA-uridine isomeraseUniRule annotation
    Gene namesi
    Name:truBUniRule annotation
    Ordered Locus Names:SYNAS_26720
    ORF Names:SYN_01783
    OrganismiSyntrophus aciditrophicus (strain SB)
    Taxonomic identifieri56780 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophaceaeSyntrophus
    ProteomesiUP000001933: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 312312tRNA pseudouridine synthase BPRO_1000084704Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi56780.SYN_01783.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2LWU1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0130.
    HOGENOMiHOG000231225.
    KOiK03177.
    OMAiYELQFIR.
    OrthoDBiEOG6358D3.

    Family and domain databases

    HAMAPiMF_01080. TruB_bact.
    InterProiIPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR014780. tRNA_psdUridine_synth_TruB.
    [Graphical view]
    PANTHERiPTHR13767. PTHR13767. 1 hit.
    PfamiPF01509. TruB_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00431. TruB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2LWU1-1 [UniParc]FASTAAdd to Basket

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    MDGILILDKS PGKTSQKVVQ EVKRILGVRK AGHAGTLDPL ATGVLPLCLN    50
    EATKLVQFLS LDDKEYRATM LLGVTTETMD IEGRITDRRE PEVDEVRIRE 100
    ALQFFTGPIS QEPPRYSAVK FKGRPLYSWA RKGVDIALPP RTVQVYSSIL 150
    EEIALPYVTF RVACSKGTYI RTLCADLGER LGCGACMSVL RRLRCGCFTL 200
    ETAVSLEDIA DGKGRETLLS RVIPLSDGLR NVAAIEISEE LSGRIRDGFQ 250
    PDGSTLREYH IPSLADGDMV KFLTSSGGLV AVARFLYASD QLAVSDMGQP 300
    AVRILRVFHD RA 312
    Length:312
    Mass (Da):34,305
    Last modified:February 21, 2006 - v1
    Checksum:i11DDAA1854061950
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000252 Genomic DNA. Translation: ABC78551.1.
    RefSeqiYP_462719.1. NC_007759.1.

    Genome annotation databases

    EnsemblBacteriaiABC78551; ABC78551; SYN_01783.
    GeneIDi3882721.
    KEGGisat:SYN_01783.
    PATRICi23866222. VBISynAci70500_2892.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000252 Genomic DNA. Translation: ABC78551.1 .
    RefSeqi YP_462719.1. NC_007759.1.

    3D structure databases

    ProteinModelPortali Q2LWU1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 56780.SYN_01783.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABC78551 ; ABC78551 ; SYN_01783 .
    GeneIDi 3882721.
    KEGGi sat:SYN_01783.
    PATRICi 23866222. VBISynAci70500_2892.

    Phylogenomic databases

    eggNOGi COG0130.
    HOGENOMi HOG000231225.
    KOi K03177.
    OMAi YELQFIR.
    OrthoDBi EOG6358D3.

    Enzyme and pathway databases

    BioCyci SACI56780:GHXT-2722-MONOMER.

    Family and domain databases

    HAMAPi MF_01080. TruB_bact.
    InterProi IPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR014780. tRNA_psdUridine_synth_TruB.
    [Graphical view ]
    PANTHERi PTHR13767. PTHR13767. 1 hit.
    Pfami PF01509. TruB_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00431. TruB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the syntrophic bacterium Syntrophus aciditrophicus: Life dependent on negative change in electrical potential."
      Gunsalus R., Rohlin L., Kim U., Krupp R., Bhattacharyya A., Campbell J., Mclerney M., Moutakki H., Rio-Hernandez L.
      Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SB.

    Entry informationi

    Entry nameiTRUB_SYNAS
    AccessioniPrimary (citable) accession number: Q2LWU1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: February 21, 2006
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3