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Q2LVV5 (SYR_SYNAS) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:SYNAS_23320
ORF Names:SYN_00994
OrganismSyntrophus aciditrophicus (strain SB) [Complete proteome] [HAMAP]
Taxonomic identifier56780 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophaceaeSyntrophus

Protein attributes

Sequence length562 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 562562Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242109

Regions

Motif137 – 14711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q2LVV5 [UniParc].

Last modified February 21, 2006. Version 1.
Checksum: CF79779665CAC2DB

FASTA56263,784
        10         20         30         40         50         60 
MQIMIGSSIK HRLTMLVKNA VDGCVAEGLL AGGNFPPVEM EMTKDTVHGD YATNFAMVMA 

        70         80         90        100        110        120 
SHARMNPRKI AEMISSHFRD GEQILEKTEI AGPGFINFFV RENVWAEQLK DIESLGNHYG 

       130        140        150        160        170        180 
SAETGRGKKV QVEFVSANPT GPLHIGHARG AVVGDVIANI LGMSGYEIFR EYYINDAGNQ 

       190        200        210        220        230        240 
MNNLGKSVWY RYQELLGRSV EFPDTCYQGD YIREIAGDIL KKDGDIHLTS NEDSNIRFFT 

       250        260        270        280        290        300 
DYAAGIILEE IKQDLKDFGI VFDKYFSERE LYVNDGVARL LADLEEKGFI YRDDETLWFK 

       310        320        330        340        350        360 
TTDFGDDKDR VVVRKNGEPT YFAADIAYHK NKYERGFDSV IDIWGADHHG YIPRMHAGIQ 

       370        380        390        400        410        420 
ALGHSKDALR VVLVQLVNLL RDGKPVAMST RSGEFVTMKE VVDEVGRDAA RYNFLMRRSD 

       430        440        450        460        470        480 
SHLDFDLEVA KRQSNENPVY YVQYAHARIC SILRMAKERG IELPSFENVE PQLLRIPEEI 

       490        500        510        520        530        540 
ALIKTLTRFP EVVEGSARTL EPHRITFYLN DLAGLFHSYY NKYKVISDDE AMTRTRLFLV 

       550        560 
KCIQTVLKNA LTLLGVSAPE KM 

« Hide

References

[1]"The genome of the syntrophic bacterium Syntrophus aciditrophicus: Life dependent on negative change in electrical potential."
Gunsalus R., Rohlin L., Kim U., Krupp R., Bhattacharyya A., Campbell J., Mclerney M., Moutakki H., Rio-Hernandez L.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SB.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000252 Genomic DNA. Translation: ABC78211.1.
RefSeqYP_462379.1. NC_007759.1.

3D structure databases

ProteinModelPortalQ2LVV5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING56780.SYN_00994.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC78211; ABC78211; SYN_00994.
GeneID3883282.
KEGGsat:SYN_00994.
PATRIC23865472. VBISynAci70500_2518.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycSACI56780:GHXT-2381-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SYNAS
AccessionPrimary (citable) accession number: Q2LVV5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: February 21, 2006
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries