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Q2LTR6 (PSD_SYNAS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:SYNAS_15940
ORF Names:SYN_00913
OrganismSyntrophus aciditrophicus (strain SB) [Complete proteome] [HAMAP]
Taxonomic identifier56780 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Syntrophobacterales › Syntrophaceae › Syntrophus

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 182182Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000262275
Chain183 – 21331Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000262276

Sites

Site182 – 1832Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1831Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2LTR6 [UniParc].

Last modified February 21, 2006. Version 1.
Checksum: E29C59A78A3E38E6

FASTA21324,147
        10         20         30         40         50         60 
MKHDSFIARE GIPFIIAFGL TTLLAVFFLE QSWIAVLPLT ATLFTCWFFR NPERHTPEGE 

        70         80         90        100        110        120 
KLIVSPADGK VIRIDEDFHH EMLSQPCSKV SIFMNVFNVH VNRVPYSGKV TKISYSPGRF 

       130        140        150        160        170        180 
LSANLDKASE QNERNAILVR TSDGKEIMTI QIAGLIARRI VCWVREEDVV KRGERFGMIR 

       190        200        210 
FGSRLEVFMP KETKILVTVG EKVKAGESPL GTF

« Hide

References

[1]"The genome of the syntrophic bacterium Syntrophus aciditrophicus: Life dependent on negative change in electrical potential."
Gunsalus R., Rohlin L., Kim U., Krupp R., Bhattacharyya A., Campbell J., Mclerney M., Moutakki H., Rio-Hernandez L.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SB.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000252 Genomic DNA. Translation: ABC77473.1.
RefSeqYP_461641.1. NC_007759.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2LTR6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3883147.
GenomeReviewsGene locus SYNAS_15940 in contig CP000252_GR.
KEGGsat:SYN_00913.
NMPDRfig|56780.10.peg.1584.
PATRIC23863862. VBISynAci70500_1723.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG541103.
OMANERVVWH.
PhylomeDBQ2LTR6.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycSACI56780:SYN_00913-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_SYNAS
AccessionPrimary (citable) accession number: Q2LTR6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: February 21, 2006
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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