Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Syntrophus aciditrophicus (strain SB)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSACI56780:GHXT-1530-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2UniRule annotation
Alternative name(s):
GroEL protein 2UniRule annotation
Protein Cpn60 2UniRule annotation
Gene namesi
Name:groL2UniRule annotation
Synonyms:groEL2UniRule annotation
Ordered Locus Names:SYNAS_14950
ORF Names:SYN_03223
OrganismiSyntrophus aciditrophicus (strain SB)
Taxonomic identifieri56780 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophaceaeSyntrophus
Proteomesi
  • UP000001933 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 54554560 kDa chaperonin 2PRO_0000257011Add
BLAST

Proteomic databases

PRIDEiQ2LTG7.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi56780.SYN_03223.

Structurei

3D structure databases

ProteinModelPortaliQ2LTG7.
SMRiQ2LTG7. Positions 2-524.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiKKQMDET.
OrthoDBiEOG6JDWBZ.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60.
InterProiIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2LTG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAKLLQYDE EARKSILNGV NALADAVKVT LGPKGRNVII DKSFGAPTVT
60 70 80 90 100
KDGVTVAKEV ELEDKFENMG AQMVREVASK TSDVAGDGTT TATILAQAIY
110 120 130 140 150
REGAKTVAAG SNPMDVKRGI EKAVAAVVTE LKNISKPTKD QKEIAQVGTI
160 170 180 190 200
SANNDETIGN IIAEAMGKVG KEGVITVEEA KGLETELEIV EGMQFDRGYL
210 220 230 240 250
SPYFVTNPEK MEVSLEDALI LIYEKKISGM KDLLPILEQI AKMGRPLLII
260 270 280 290 300
AEDIEGEALA TLVVNKIRGT LHVAAVKAPG FGDRRKAMLE DIAILTGGTV
310 320 330 340 350
ISEDMGYKLE NTRLEDLGRA KRIQIDKDNT TIIDGAGERA ALEGRVKQIR
360 370 380 390 400
AQIDETTSDY DREKLQERLA KLVGGVAVIK VGAATETEMK EKKARVEDAL
410 420 430 440 450
NATRAAVEEG IVPGGGVAYI RTLPILEALK LEGDEQVGVN IVRKALEEPL
460 470 480 490 500
KMIAANAGME GTIVVEKVKE QSGAFGFNAR TEVYEDMIEA GVIDPTKVTR
510 520 530 540
FALQNAASVA SLMLTTQCMI AEKPEEKGAG MPGMPPGGGY PGMGM
Length:545
Mass (Da):58,258
Last modified:February 21, 2006 - v1
Checksum:i113A4D20EE092C0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000252 Genomic DNA. Translation: ABC77374.1.
RefSeqiWP_011417396.1. NC_007759.1.

Genome annotation databases

EnsemblBacteriaiABC77374; ABC77374; SYN_03223.
KEGGisat:SYN_03223.
PATRICi23863644. VBISynAci70500_1618.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000252 Genomic DNA. Translation: ABC77374.1.
RefSeqiWP_011417396.1. NC_007759.1.

3D structure databases

ProteinModelPortaliQ2LTG7.
SMRiQ2LTG7. Positions 2-524.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi56780.SYN_03223.

Proteomic databases

PRIDEiQ2LTG7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC77374; ABC77374; SYN_03223.
KEGGisat:SYN_03223.
PATRICi23863644. VBISynAci70500_1618.

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiKKQMDET.
OrthoDBiEOG6JDWBZ.

Enzyme and pathway databases

BioCyciSACI56780:GHXT-1530-MONOMER.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60.
InterProiIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of the syntrophic bacterium Syntrophus aciditrophicus: Life dependent on negative change in electrical potential."
    Gunsalus R., Rohlin L., Kim U., Krupp R., Bhattacharyya A., Campbell J., Mclerney M., Moutakki H., Rio-Hernandez L.
    Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SB.

Entry informationi

Entry nameiCH602_SYNAS
AccessioniPrimary (citable) accession number: Q2LTG7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: February 21, 2006
Last modified: December 9, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.