ID   Q2LSY1_SYNAS            Unreviewed;       653 AA.
AC   Q2LSY1;
DT   21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT   21-FEB-2006, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:ABC77195.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:ABC77195.1};
GN   ORFNames=SYN_02853 {ECO:0000313|EMBL:ABC77195.1};
OS   Syntrophus aciditrophicus (strain SB).
OC   Bacteria; Thermodesulfobacteriota; Syntrophia; Syntrophales; Syntrophaceae;
OC   Syntrophus.
OX   NCBI_TaxID=56780 {ECO:0000313|EMBL:ABC77195.1, ECO:0000313|Proteomes:UP000001933};
RN   [1] {ECO:0000313|EMBL:ABC77195.1, ECO:0000313|Proteomes:UP000001933}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB {ECO:0000313|EMBL:ABC77195.1,
RC   ECO:0000313|Proteomes:UP000001933};
RX   PubMed=17442750; DOI=10.1073/pnas.0610456104;
RA   McInerney M.J., Rohlin L., Mouttaki H., Kim U., Krupp R.S.,
RA   Rios-Hernandez L., Sieber J., Struchtemeyer C.G., Bhattacharyya A.,
RA   Campbell J.W., Gunsalus R.P.;
RT   "The genome of Syntrophus aciditrophicus: life at the thermodynamic limit
RT   of microbial growth.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:7600-7605(2007).
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DR   EMBL; CP000252; ABC77195.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2LSY1; -.
DR   STRING; 56780.SYN_02853; -.
DR   KEGG; sat:SYN_02853; -.
DR   eggNOG; COG3072; Bacteria.
DR   HOGENOM; CLU_013280_1_0_7; -.
DR   InParanoid; Q2LSY1; -.
DR   Proteomes; UP000001933; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IEA:InterPro.
DR   InterPro; IPR000274; Adenylate_cyclase_1.
DR   InterPro; IPR024685; Adenylate_cyclase_1_N.
DR   PANTHER; PTHR38760; ADENYLATE CYCLASE; 1.
DR   PANTHER; PTHR38760:SF1; ADENYLATE CYCLASE; 1.
DR   Pfam; PF12633; Adenyl_cycl_N; 1.
DR   Pfam; PF01295; Adenylate_cycl; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:ABC77195.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001933}.
FT   DOMAIN          32..231
FT                   /note="Adenylate cyclase class-I N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12633"
SQ   SEQUENCE   653 AA;  76328 MW;  A569B0F213086C48 CRC64;
     MDNIRKTAID LCRSREDAGI RMALSRILIQ NKSIFLEYNR FRKRLFSELA PKDSEIILYL
     LPWMLSVNDV SIPGYVDHIK QNFRVFNIET EKDILKRERL FKKTFHIRND LTVLKPAEKS
     LPVEGIYTIG SVGTISQTSS SDCDLWICID KTLYDEEAFD LLTLKIDRIK DWMDSRLKMP
     VCFFLCDVED IRACRFGGVD CESCGSTQKK VLKEEFYRTA ILTAGKIPLW WVAWDRRQTL
     CYDDAVREWQ SAPSVYYDLI DLGNLDFIDK RESFGAALWQ FNKSLTHPLK SILKMLLLKM
     FLESPKEELL CHRFRRLILD QPRKPHSFVD PGAFTLIAVL DFYQNMDPQT LQFILKCFYL
     RYKVKLFSRT MTVKEETALE LFRRYGLDRE TIYELNRFSS WTYSSQIRFG EFIVLLLVDI
     YKDIAHIARD VTGDVAAQDL TILGQKLSAS LKKKPHKIPV LSKPLETLKM PSLTLRFCEN
     RWQVFPDNDD GAMIVEKRDL VYCLAYLAWN DLYFPGQLRM LPNPTSAAMQ EIINLLQKIR
     EVFGVYDVSS IDFQNFLQPE HTEKLLIIIN FAAPPHADVI HTLSVIRLNN WGELFVNRFT
     LQERFISFLE NIAESSYNTV EFFHVQKNAP HSGKLLAKAR RLVSKYFVLV DRK
//