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Q2LRD0

- G6PI_SYNAS

UniProt

Q2LRD0 - G6PI_SYNAS

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, SYNAS_07620, SYN_02950
Organism
Syntrophus aciditrophicus (strain SB)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donor By similarity
Active sitei387 – 3871 By similarity
Active sitei507 – 5071 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciSACI56780:GHXT-783-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:SYNAS_07620
ORF Names:SYN_02950
OrganismiSyntrophus aciditrophicus (strain SB)
Taxonomic identifieri56780 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophaceaeSyntrophus
ProteomesiUP000001933: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 546546Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000252659Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi56780.SYN_02950.

Structurei

3D structure databases

ProteinModelPortaliQ2LRD0.
SMRiQ2LRD0. Positions 6-544.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiMIALTHY.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2LRD0-1 [UniParc]FASTAAdd to Basket

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MTASKKLTGC QAWKALAAHR RNWKLHLRDL FAGDPGRGER MTAEAVGLFL    50
DYSKNFVTDE TLKLLLRLAE ETGLRGRIEA LFRGEKINLT ENRAALHVAL 100
RSPKGTSIVV DGENVVPQVH DVLDRMAAFA VQVRSGSWKG HSGKGIRNVV 150
NIGIGGSDLG PVMAYEALKY YSDRSLTFRF VSNIDGTDFA EAVQDLDAAE 200
TLFIVASKTF TTLETMTNAS TARAWLLQGF KGDEKAVAKH FVAVSTNTAE 250
VAKFGIDTAN MFGFWNWVGG RYSMDSAIGL STMLAIGPDN FRDMLAGFHA 300
MDVHFRTAPF GVNLPVLMGL LTIWYNNFFA AETVAVLPYE QYLKRFPAYL 350
QQLTMESNGK RVTLDGMEVD YQTSPIYWGE PGTNGQHSFY QLIHQGTKLI 400
PCDFIAFVEP LHPLGRHHDL LMANVFAQAE ALAFGRTLEE VTSEGIPAWL 450
APHKVFEGNR PSNTILAQRL TPETLGKLVA LYEHSVFTQS AIWNINPFDQ 500
WGVELGKVLA QRVITELESR EEPELGHDSS TNAMIRRYRK FRERME 546
Length:546
Mass (Da):60,934
Last modified:February 21, 2006 - v1
Checksum:i5E29E4684DAE93A9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000252 Genomic DNA. Translation: ABC76641.1.
RefSeqiYP_460809.1. NC_007759.1.

Genome annotation databases

EnsemblBacteriaiABC76641; ABC76641; SYN_02950.
GeneIDi3885170.
KEGGisat:SYN_02950.
PATRICi23862031. VBISynAci70500_0826.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000252 Genomic DNA. Translation: ABC76641.1 .
RefSeqi YP_460809.1. NC_007759.1.

3D structure databases

ProteinModelPortali Q2LRD0.
SMRi Q2LRD0. Positions 6-544.
ModBasei Search...

Protein-protein interaction databases

STRINGi 56780.SYN_02950.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC76641 ; ABC76641 ; SYN_02950 .
GeneIDi 3885170.
KEGGi sat:SYN_02950.
PATRICi 23862031. VBISynAci70500_0826.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi MIALTHY.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci SACI56780:GHXT-783-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of the syntrophic bacterium Syntrophus aciditrophicus: Life dependent on negative change in electrical potential."
    Gunsalus R., Rohlin L., Kim U., Krupp R., Bhattacharyya A., Campbell J., Mclerney M., Moutakki H., Rio-Hernandez L.
    Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SB.

Entry informationi

Entry nameiG6PI_SYNAS
AccessioniPrimary (citable) accession number: Q2LRD0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: February 21, 2006
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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