Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2LR71

- UVRC_SYNAS

UniProt

Q2LR71 - UVRC_SYNAS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

UvrABC system protein C

Gene

uvrC

Organism
Syntrophus aciditrophicus (strain SB)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. excinuclease ABC activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. nucleotide-excision repair Source: UniProtKB-HAMAP
  2. SOS response Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Excision nuclease

Keywords - Biological processi

DNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciSACI56780:GHXT-720-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:SYNAS_07050
ORF Names:SYN_01348
OrganismiSyntrophus aciditrophicus (strain SB)
Taxonomic identifieri56780 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophaceaeSyntrophus
ProteomesiUP000001933: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
  2. excinuclease repair complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 618618UvrABC system protein CPRO_0000264969Add
BLAST

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi56780.SYN_01348.

Structurei

3D structure databases

ProteinModelPortaliQ2LR71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 9379GIY-YIGUniRule annotationAdd
BLAST
Domaini203 – 23836UVRUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation
Contains 1 GIY-YIG domain.UniRule annotation
Contains 1 UVR domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0322.
HOGENOMiHOG000279960.
KOiK03703.
OMAiQTIASCV.
OrthoDBiEOG6K13R9.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC.
InterProiIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamiPF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTiSM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2LR71 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNRQQLEGRI DIAPRTPGVY LMKDAAGKIL YVGKAKNLKS RTRAYFSGTD
60 70 80 90 100
SRAMIPFLVS RIHDIEFILT ETEKEALILE NNLIKEHHPR YNICFRDDKA
110 120 130 140 150
YFNIRADLNE PFPRFQLVRR PRKDGAKYFG PYPSSASARE TLQFLQSIFP
160 170 180 190 200
LRTCRDAELK SRTRPCLEYQ IKRCLAPCVG RINSEDYLQM VRDGVSFLEG
210 220 230 240 250
RGNNLLRELR ERMKMAAEQM NYEEAAFLRD RIRAIEETLE RQRMVSMTFK
260 270 280 290 300
DQDIFGLYRE GHLIQVCILL IRQGKILGSR LLPLLKFEGE TADMLSSLLM
310 320 330 340 350
QYYDQSVDIP QEILIPASIE DRQVIREWLE EKRGKGLSIL IPRKGRGLEL
360 370 380 390 400
LHIAEQNAEH GFKMERKSLD DSDESLRLLM ERLHLRRFPR KIEAFDISNI
410 420 430 440 450
GGRLAVAAMV TFQDGRPLKS GYRRFRIRTV HGADDYAMMY EALKRRYQGK
460 470 480 490 500
ENLPDLIVVD GGKGQLAVAF SLLKDLSISG QDVIGLAKER VNGVTVQGGV
510 520 530 540 550
NKSEDRVYLP HKKEALYLSR WPAVLFLLQR IRDEAHRFAV SYHRSLKTRS
560 570 580 590 600
DFMSLLDDIP GVGEVRKKAL LLSFGDLARI REATVEELTQ VEGIGKDLGE
610
KIHAFLHNDQ RSVEPSTG
Length:618
Mass (Da):71,119
Last modified:February 21, 2006 - v1
Checksum:iD90A769D1192C88D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000252 Genomic DNA. Translation: ABC76584.1.
RefSeqiYP_460752.1. NC_007759.1.

Genome annotation databases

EnsemblBacteriaiABC76584; ABC76584; SYN_01348.
GeneIDi3884766.
KEGGisat:SYN_01348.
PATRICi23861901. VBISynAci70500_0767.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000252 Genomic DNA. Translation: ABC76584.1 .
RefSeqi YP_460752.1. NC_007759.1.

3D structure databases

ProteinModelPortali Q2LR71.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 56780.SYN_01348.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC76584 ; ABC76584 ; SYN_01348 .
GeneIDi 3884766.
KEGGi sat:SYN_01348.
PATRICi 23861901. VBISynAci70500_0767.

Phylogenomic databases

eggNOGi COG0322.
HOGENOMi HOG000279960.
KOi K03703.
OMAi QTIASCV.
OrthoDBi EOG6K13R9.

Enzyme and pathway databases

BioCyci SACI56780:GHXT-720-MONOMER.

Family and domain databases

Gene3Di 3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPi MF_00203. UvrC.
InterProi IPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view ]
Pfami PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view ]
SMARTi SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view ]
SUPFAMi SSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsi TIGR00194. uvrC. 1 hit.
PROSITEi PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of the syntrophic bacterium Syntrophus aciditrophicus: Life dependent on negative change in electrical potential."
    Gunsalus R., Rohlin L., Kim U., Krupp R., Bhattacharyya A., Campbell J., Mclerney M., Moutakki H., Rio-Hernandez L.
    Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SB.

Entry informationi

Entry nameiUVRC_SYNAS
AccessioniPrimary (citable) accession number: Q2LR71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: February 21, 2006
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3