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Q2LR71

- UVRC_SYNAS

UniProt

Q2LR71 - UVRC_SYNAS

Protein

UvrABC system protein C

Gene

uvrC

Organism
Syntrophus aciditrophicus (strain SB)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (21 Feb 2006)
      Previous versions | rss
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    Functioni

    The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. excinuclease ABC activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. nucleotide-excision repair Source: UniProtKB-HAMAP
    2. SOS response Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Excision nuclease

    Keywords - Biological processi

    DNA damage, DNA excision, DNA repair, SOS response

    Enzyme and pathway databases

    BioCyciSACI56780:GHXT-720-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UvrABC system protein CUniRule annotation
    Short name:
    Protein UvrCUniRule annotation
    Alternative name(s):
    Excinuclease ABC subunit CUniRule annotation
    Gene namesi
    Name:uvrCUniRule annotation
    Ordered Locus Names:SYNAS_07050
    ORF Names:SYN_01348
    OrganismiSyntrophus aciditrophicus (strain SB)
    Taxonomic identifieri56780 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaSyntrophobacteralesSyntrophaceaeSyntrophus
    ProteomesiUP000001933: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. excinuclease repair complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 618618UvrABC system protein CPRO_0000264969Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with UvrB in an incision complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi56780.SYN_01348.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2LR71.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini15 – 9379GIY-YIGUniRule annotationAdd
    BLAST
    Domaini203 – 23836UVRUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the UvrC family.UniRule annotation
    Contains 1 GIY-YIG domain.UniRule annotation
    Contains 1 UVR domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0322.
    HOGENOMiHOG000279960.
    KOiK03703.
    OMAiQTIASCV.
    OrthoDBiEOG6K13R9.

    Family and domain databases

    Gene3Di3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPiMF_00203. UvrC.
    InterProiIPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view]
    PfamiPF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view]
    SMARTiSM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view]
    SUPFAMiSSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsiTIGR00194. uvrC. 1 hit.
    PROSITEiPS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2LR71-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNRQQLEGRI DIAPRTPGVY LMKDAAGKIL YVGKAKNLKS RTRAYFSGTD    50
    SRAMIPFLVS RIHDIEFILT ETEKEALILE NNLIKEHHPR YNICFRDDKA 100
    YFNIRADLNE PFPRFQLVRR PRKDGAKYFG PYPSSASARE TLQFLQSIFP 150
    LRTCRDAELK SRTRPCLEYQ IKRCLAPCVG RINSEDYLQM VRDGVSFLEG 200
    RGNNLLRELR ERMKMAAEQM NYEEAAFLRD RIRAIEETLE RQRMVSMTFK 250
    DQDIFGLYRE GHLIQVCILL IRQGKILGSR LLPLLKFEGE TADMLSSLLM 300
    QYYDQSVDIP QEILIPASIE DRQVIREWLE EKRGKGLSIL IPRKGRGLEL 350
    LHIAEQNAEH GFKMERKSLD DSDESLRLLM ERLHLRRFPR KIEAFDISNI 400
    GGRLAVAAMV TFQDGRPLKS GYRRFRIRTV HGADDYAMMY EALKRRYQGK 450
    ENLPDLIVVD GGKGQLAVAF SLLKDLSISG QDVIGLAKER VNGVTVQGGV 500
    NKSEDRVYLP HKKEALYLSR WPAVLFLLQR IRDEAHRFAV SYHRSLKTRS 550
    DFMSLLDDIP GVGEVRKKAL LLSFGDLARI REATVEELTQ VEGIGKDLGE 600
    KIHAFLHNDQ RSVEPSTG 618
    Length:618
    Mass (Da):71,119
    Last modified:February 21, 2006 - v1
    Checksum:iD90A769D1192C88D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000252 Genomic DNA. Translation: ABC76584.1.
    RefSeqiYP_460752.1. NC_007759.1.

    Genome annotation databases

    EnsemblBacteriaiABC76584; ABC76584; SYN_01348.
    GeneIDi3884766.
    KEGGisat:SYN_01348.
    PATRICi23861901. VBISynAci70500_0767.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000252 Genomic DNA. Translation: ABC76584.1 .
    RefSeqi YP_460752.1. NC_007759.1.

    3D structure databases

    ProteinModelPortali Q2LR71.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 56780.SYN_01348.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABC76584 ; ABC76584 ; SYN_01348 .
    GeneIDi 3884766.
    KEGGi sat:SYN_01348.
    PATRICi 23861901. VBISynAci70500_0767.

    Phylogenomic databases

    eggNOGi COG0322.
    HOGENOMi HOG000279960.
    KOi K03703.
    OMAi QTIASCV.
    OrthoDBi EOG6K13R9.

    Enzyme and pathway databases

    BioCyci SACI56780:GHXT-720-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPi MF_00203. UvrC.
    InterProi IPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view ]
    Pfami PF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view ]
    SMARTi SM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsi TIGR00194. uvrC. 1 hit.
    PROSITEi PS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the syntrophic bacterium Syntrophus aciditrophicus: Life dependent on negative change in electrical potential."
      Gunsalus R., Rohlin L., Kim U., Krupp R., Bhattacharyya A., Campbell J., Mclerney M., Moutakki H., Rio-Hernandez L.
      Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SB.

    Entry informationi

    Entry nameiUVRC_SYNAS
    AccessioniPrimary (citable) accession number: Q2LR71
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: February 21, 2006
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3