ID   Q2LR59_SYNAS            Unreviewed;       686 AA.
AC   Q2LR59;
DT   21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT   21-FEB-2006, sequence version 1.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ABC76570.1};
GN   ORFNames=SYN_00432 {ECO:0000313|EMBL:ABC76570.1};
OS   Syntrophus aciditrophicus (strain SB).
OC   Bacteria; Thermodesulfobacteriota; Syntrophia; Syntrophales; Syntrophaceae;
OC   Syntrophus.
OX   NCBI_TaxID=56780 {ECO:0000313|EMBL:ABC76570.1, ECO:0000313|Proteomes:UP000001933};
RN   [1] {ECO:0000313|EMBL:ABC76570.1, ECO:0000313|Proteomes:UP000001933}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB {ECO:0000313|EMBL:ABC76570.1,
RC   ECO:0000313|Proteomes:UP000001933};
RX   PubMed=17442750; DOI=10.1073/pnas.0610456104;
RA   McInerney M.J., Rohlin L., Mouttaki H., Kim U., Krupp R.S.,
RA   Rios-Hernandez L., Sieber J., Struchtemeyer C.G., Bhattacharyya A.,
RA   Campbell J.W., Gunsalus R.P.;
RT   "The genome of Syntrophus aciditrophicus: life at the thermodynamic limit
RT   of microbial growth.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:7600-7605(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000252; ABC76570.1; -; Genomic_DNA.
DR   RefSeq; WP_011416604.1; NC_007759.1.
DR   AlphaFoldDB; Q2LR59; -.
DR   STRING; 56780.SYN_00432; -.
DR   KEGG; sat:SYN_00432; -.
DR   eggNOG; COG0840; Bacteria.
DR   eggNOG; COG2972; Bacteria.
DR   HOGENOM; CLU_000445_107_19_7; -.
DR   InParanoid; Q2LR59; -.
DR   OrthoDB; 5428110at2; -.
DR   Proteomes; UP000001933; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd12914; PDC1_DGC_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001933};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        292..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          317..370
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          414..650
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   686 AA;  73575 MW;  603F6288EE4101B0 CRC64;
     MNMKLGTKLL TGGLLVVLAP LVVIGIASVY KSMDSISSIA YEEMTNVSNS LASTIDLGLS
     EELRLSQAIS FSNSVKAAAE KVAEVGREES RSEIALVERE LVRIREAAGN RYETIVLFGR
     DGIVYADAVQ GKDHGIDASD RDYFKKAMQG NCNFSDVFRS KATGQLISMT ACPIFSGRTN
     KIIGVVGCAI NVGYLIDMVN EIKIGQTGYS LLVNEEGTVL AHPDKESILK LNYKKLKGME
     RVSEKAALQG GGVANYEFEG EKKVAAFSNI KTTGWTAFTT ISRKELLKPA VFTGNLIAVI
     GFISLLLAAA FFYFFSRSLT RPLEKVVSAA EQIAEGDLSV QISDENRQDE IGMLARAFMK
     MTQSLQEKAG VLQQIAAGNL TVEMKTPSDR DVMGKAFAAM ISALRAEMQS IREAVNVIAS
     SATQISASTT ELASAASQTA SAVSETTSTV EEVKQTAHLS TQKATHVFDS AQKATEVSQQ
     GRKAIDLAVE GMNFIRTQTD SISESIVKLS ERSQAIGEII ATVNDIADQS NLLAVNAAIE
     AAKAGDQGKG FAVVAQEVRN LAEQSKQATS QVRTILNEVQ KAVGEAVMST EQEIKAVEAG
     VRQTSEAGNS FRRLSDTIEE SAQAATQITA SSQQQLVGMD QVVLAITNIS QASSQNVAGA
     KQVETAAQNL HDLGQQLKQL IDRYRL
//