Q2LQ43 (Q2LQ43_SYNAS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thioredoxin reductase RuleBase RU003881
EC=1.8.1.9 RuleBase RU003881

Gene names

Ordered Locus Names:	SYNAS_02430
ORF Names:	SYN_01439 EMBL ABC76122.1

Organism

Syntrophus aciditrophicus (strain SB) [Complete proteome] [HAMAP]

Taxonomic identifier

56780 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Syntrophobacterales › Syntrophaceae › Syntrophus

Protein attributes

Sequence length	324 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. RuleBase RU003881
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003881
Sequence similarities	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003880

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003880
Ligand	FAD RuleBase RU003880 Flavoprotein RuleBase RU003880
Molecular function	Oxidoreductase RuleBase RU003880
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	removal of superoxide radicals Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro thioredoxin-disulfide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2LQ43 [UniParc]. Last modified February 21, 2006. Version 1. Checksum: 1E2D9E6F44570D15	FASTA	324	34,818
	10 20 30 40 50 60 MEGNESLKLV YDIIVVGGGP AGLTAGLYAA RGGLKALLLE GESSVSQITV TDLVENYPGF 70 80 90 100 110 120 PEGINGYDLV ERFRTQAGRF GLKILTEDIR AIDAGAAEHW IVSGRDSAYE ALSVILATGA 130 140 150 160 170 180 NWRHLGVPGE AAFTGKGVSY CATCDGPFYR DREVVVVGGG DTAVQEALFL TRFARKVTIV 190 200 210 220 230 240 HRRDRLRATP ILQERAFAHE RIDFAWDSVV EEIQGGEFVE GVRIRNLKNP EKSRIIPADG 250 260 270 280 290 300 AFIFVGLTPN TGFVRGLVNC DENGYILADA EMKTSVKGIF ACGDCISKLL RQVVTACGDA 310 320 ATAAFSAQLH VEALKGEDYG GRKA

References

[1]

"The genome of the syntrophic bacterium Syntrophus aciditrophicus: Life dependent on negative change in electrical potential." Gunsalus R., Rohlin L., Kim U., Krupp R., Bhattacharyya A., Campbell J., Mclerney M., Moutakki H., Rio-Hernandez L. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000252 Genomic DNA. Translation: ABC76122.1.
RefSeq	YP_460290.1. NC_007759.1.
3D structure databases
ProteinModelPortal	Q2LQ43.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2LQ43.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3885221.
GenomeReviews	Gene locus SYNAS_02430 in contig CP000252_GR.
KEGG	sat:SYN_01439.
NMPDR	fig|56780.10.peg.242.
PATRIC	23860881. VBISynAci70500_0268.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0492.
HOGENOM	HBG669726.
OMA	AVEEAMY.
PhylomeDB	Q2LQ43.
Enzyme and pathway databases
BioCyc	SACI56780:SYN_01439-MONOMER.
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. [Graphical view]
KO	K00384.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
TIGRFAMs	TIGR01292. TRX_reduct. 1 hit.
PROSITE	PS00573. PYRIDINE_REDOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2LQ43_SYNAS

Accession

Primary (citable) accession number: Q2LQ43

Entry history

Integrated into UniProtKB/TrEMBL:	February 21, 2006
Last sequence update:	February 21, 2006
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)