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Protein

Cytochrome c oxidase subunit 3

Gene

cox3

Organism
Dictyostelium citrinum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:cox3
Encoded oniMitochondrion
OrganismiDictyostelium citrinum (Slime mold)
Taxonomic identifieri361072 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Transmembranei96 – 116HelicalSequence analysisAdd BLAST21
Transmembranei132 – 152HelicalSequence analysisAdd BLAST21
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Transmembranei321 – 341HelicalSequence analysisAdd BLAST21
Transmembranei356 – 376HelicalSequence analysisAdd BLAST21
Transmembranei408 – 428HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003123871 – 431Cytochrome c oxidase subunit 3Add BLAST431

Proteomic databases

PRIDEiQ2LCP9

Structurei

3D structure databases

ProteinModelPortaliQ2LCP9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

CDDicd01665 Cyt_c_Oxidase_III, 1 hit
Gene3Di1.20.120.80, 2 hits
InterProiView protein in InterPro
IPR024791 Cyt_c/ubiquinol_Oxase_su3
IPR033945 Cyt_c_oxase_su3_dom
IPR000298 Cyt_c_oxidase-like_su3
IPR035973 Cyt_c_oxidase_su3-like_sf
IPR013833 Cyt_c_oxidase_su3_a-hlx
PANTHERiPTHR11403 PTHR11403, 1 hit
PfamiView protein in Pfam
PF00510 COX3, 2 hits
SUPFAMiSSF81452 SSF81452, 2 hits
PROSITEiView protein in PROSITE
PS50253 COX3, 1 hit

Sequencei

Sequence statusi: Complete.

Q2LCP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRFFENLFS QTERSVLNTG KKVGAGIAAG EWKNTEWGYP IATQEVIFLA
60 70 80 90 100
KVFQPQHVKR HPYHIVRGTI APLAVTLPLA FFVLNYFGVI SSKIGFVIAL
110 120 130 140 150
SSFIGGLTIW AISIVFDSLY DQQHTYEVKR GLVMGMMMFI ISEIMFFFSF
160 170 180 190 200
FWSYFYISLS PNIAIGCVWP PYGLTVYSYM GLPLLNTVLL LLSGAILTDG
210 220 230 240 250
YTILTEQKAV HENNEKVIAV EEAFTNLMNL YTKKQSINTL TFVDERREKF
260 270 280 290 300
FAKNDQNAEK KEIAISAGVK ELRDLDWDLY FFENPQNMEP NYKAPTDLSV
310 320 330 340 350
IEYALITIFL KKRNKVIKTR LYFTLVCAVV FLFCQGYEYY FAPFSMNDGI
360 370 380 390 400
YGSLFFLLTG FHGFHVLVGS ILIGIITIRF IVGNFDLLNV GTKFQIFKNK
410 420 430
STGFACTLFY WHFVDIVWIF LYIVIYWWGS R
Length:431
Mass (Da):49,659
Last modified:February 21, 2006 - v1
Checksum:iCEAE1DA818BFBA3A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ336395 Genomic DNA Translation: ABC60394.1
RefSeqiYP_492643.1, NC_007787.2

Genome annotation databases

GeneIDi3912631

Similar proteinsi

Entry informationi

Entry nameiCOX3_DICCI
AccessioniPrimary (citable) accession number: Q2LCP9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: February 21, 2006
Last modified: May 23, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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