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Q2LCP9

- COX3_DICCI

UniProt

Q2LCP9 - COX3_DICCI

Protein

Cytochrome c oxidase subunit 3

Gene

cox3

Organism
Dictyostelium citrinum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (21 Feb 2006)
      Previous versions | rss
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    Functioni

    Subunits I, II and III form the functional core of the enzyme complex.By similarity

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide III
    Gene namesi
    Name:cox3
    Encoded oniMitochondrion
    OrganismiDictyostelium citrinum (Slime mold)
    Taxonomic identifieri361072 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 431431Cytochrome c oxidase subunit 3PRO_0000312387Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ2LCP9.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei70 – 9021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei96 – 11621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei132 – 15221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei176 – 19621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei321 – 34121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei356 – 37621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei408 – 42821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Family and domain databases

    Gene3Di1.20.120.80. 2 hits.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 2 hits.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 2 hits.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2LCP9-1 [UniParc]FASTAAdd to Basket

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    MKRFFENLFS QTERSVLNTG KKVGAGIAAG EWKNTEWGYP IATQEVIFLA    50
    KVFQPQHVKR HPYHIVRGTI APLAVTLPLA FFVLNYFGVI SSKIGFVIAL 100
    SSFIGGLTIW AISIVFDSLY DQQHTYEVKR GLVMGMMMFI ISEIMFFFSF 150
    FWSYFYISLS PNIAIGCVWP PYGLTVYSYM GLPLLNTVLL LLSGAILTDG 200
    YTILTEQKAV HENNEKVIAV EEAFTNLMNL YTKKQSINTL TFVDERREKF 250
    FAKNDQNAEK KEIAISAGVK ELRDLDWDLY FFENPQNMEP NYKAPTDLSV 300
    IEYALITIFL KKRNKVIKTR LYFTLVCAVV FLFCQGYEYY FAPFSMNDGI 350
    YGSLFFLLTG FHGFHVLVGS ILIGIITIRF IVGNFDLLNV GTKFQIFKNK 400
    STGFACTLFY WHFVDIVWIF LYIVIYWWGS R 431
    Length:431
    Mass (Da):49,659
    Last modified:February 21, 2006 - v1
    Checksum:iCEAE1DA818BFBA3A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ336395 Genomic DNA. Translation: ABC60394.1.
    RefSeqiYP_492643.1. NC_007787.2.

    Genome annotation databases

    GeneIDi3912631.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ336395 Genomic DNA. Translation: ABC60394.1 .
    RefSeqi YP_492643.1. NC_007787.2.

    3D structure databases

    ProteinModelPortali Q2LCP9.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3912631.

    Family and domain databases

    Gene3Di 1.20.120.80. 2 hits.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 2 hits.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 2 hits.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Mitochondrial genome evolution in the social amoebae."
      Heidel A.J., Gloeckner G.
      Mol. Biol. Evol. 25:1440-1450(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiCOX3_DICCI
    AccessioniPrimary (citable) accession number: Q2LCP9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 4, 2007
    Last sequence update: February 21, 2006
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3