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Q2LAE2

- Q2LAE2_HUMAN

UniProt

Q2LAE2 - Q2LAE2_HUMAN

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Protein
Submitted name: Intersectin 1 short form
Gene
ITSN1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Intersectin 1 short formImported
Gene namesi
Name:ITSN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ2LAE2.

Expressioni

Gene expression databases

BgeeiQ2LAE2.

Structurei

3D structure databases

ProteinModelPortaliQ2LAE2.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG052159.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF14604. SH3_9. 3 hits.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 3 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 3 hits.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q2LAE2-1 [UniParc]FASTAAdd to Basket

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QFPTPFGGSL DIWAITVEER AKHDQQFHSL KPISGFITGD QARNFFFQSG     50
LPQPVLAQIW ALADMNNDGR MDQVEFSIAM KLIKLKLQGY QLPSALPPVM 100
KQQPVAISSA PAFGMGGIAS MPPLTAVAPV PMGSIPVVGM SPTLVSSVPT 150
AAVPPLANGA PPVIQPLPAF AHPAATLPKS SSFSRSGPGS QLNTKLQKAQ 200
SFDVASVPPV AEWAVPQSSR LKYRQLFNSH DKTMSGHLTG PQARTILMQS 250
SLPQAQLASI WNLSDIDQDG KLTAEEFILA MHLIDVAMSG QPLPPVLPPE 300
YIPPSFRRVR SGSGISVISS TSVDQRLPEE PVLEDEQQQL EKKLPVTFED 350
KKRENFERGN LELEKRRQAL LEQQRKEQER LAQLERAEQE RKERERQEQE 400
RKRQLELEKQ LEKQRELERQ REEERRKEIE RREAAKRELE RQRQLEWERN 450
RRQELLNQRN KEQEDIVVLK AKKKTLEFEL EALNDKKHQL EGKLQDIRCR 500
LTTQRQEIES TNKSRELRIA EITHLQQQLQ ESQQMLGRLI PEKQILNDQL 550
KQVQQNSLHR DSLVTLKRAL EAKELARQHL RDQLDEVEKE TRSKLQEIDI 600
FNNQLKELRE IHNKQQLQKQ KSMEAERLKQ KEQERKIIEL EKQKEEAQRR 650
AQERDKQWLE HVQQEDEHQR PRKLHEEEKL KREESVKKKD GEEKGKQEAQ 700
DKLGRLFHQH QEPAKPAVQA PWSTAEKGPL TISAQENVKV VYYRALYPFE 750
SRSHDEITIQ PGDIVMVDES QTGEPGWLGG ELKGKTGWFP ANYAEKIPEN 800
EVPAPVKPVT DSTSAPAPKL ALRETPAPLA VTSSEPSTTP NNWADFSSTW 850
PTSTNEKPET DNWDAWAAQP SLTVPSAGQL RQRSAFTPAT ATGSSPSPVL 900
GQGEKVEGLQ AQALYPWRAK KDNHLNFNKN DVITVLEQQD MWWFGEVQGQ 950
KGWFPKSYVK LISGPIRKST SMDSGSSESP ASLKRVASPA AKPVVSGEEF 1000
IAMYTYESSE QGDLTFQQGD VILVTKKDGD WWTGTVGDKA GVFPSNYVRL 1050
KDSEGSGTAG KTGSLGKKPG PSCNVK 1076
Length:1,076
Mass (Da):121,644
Last modified:February 21, 2006 - v1
Checksum:iFBFBD9081E1BE3BF
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ340865 mRNA. Translation: ABC69037.1.
UniGeneiHs.160324.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ340865 mRNA. Translation: ABC69037.1 .
UniGenei Hs.160324.

3D structure databases

ProteinModelPortali Q2LAE2.
ModBasei Search...

Proteomic databases

PRIDEi Q2LAE2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG052159.

Gene expression databases

Bgeei Q2LAE2.

Family and domain databases

Gene3Di 1.10.238.10. 2 hits.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR001452. SH3_domain.
[Graphical view ]
Pfami PF14604. SH3_9. 3 hits.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 3 hits.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 3 hits.
PROSITEi PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structural diversity and differential expression of novel human intersectin 1 isoforms."
    Kropyvko S., Gerasymchuk D., Skrypkina I., Dergai M., Dergai O., Nikolaienko O., Rynditch A., Tsyba L.
    Mol. Biol. Rep. 37:2789-2796(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ2LAE2_HUMAN
AccessioniPrimary (citable) accession number: Q2LAE2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 21, 2006
Last sequence update: February 21, 2006
Last modified: June 11, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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