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Q2LAE2

- Q2LAE2_HUMAN

UniProt

Q2LAE2 - Q2LAE2_HUMAN

Protein
Submitted name:

Intersectin 1 short form

Gene

ITSN1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (21 Feb 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Intersectin 1 short formImported
    Gene namesi
    Name:ITSN1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Proteomic databases

    PRIDEiQ2LAE2.

    Expressioni

    Gene expression databases

    BgeeiQ2LAE2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2LAE2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG052159.

    Family and domain databases

    Gene3Di1.10.238.10. 2 hits.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR001452. SH3_domain.
    [Graphical view]
    PfamiPF14604. SH3_9. 3 hits.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00054. EFh. 2 hits.
    SM00027. EH. 2 hits.
    SM00326. SH3. 3 hits.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 3 hits.
    PROSITEiPS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 2 hits.
    PS50031. EH. 2 hits.
    PS50002. SH3. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q2LAE2-1 [UniParc]FASTAAdd to Basket

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    QFPTPFGGSL DIWAITVEER AKHDQQFHSL KPISGFITGD QARNFFFQSG     50
    LPQPVLAQIW ALADMNNDGR MDQVEFSIAM KLIKLKLQGY QLPSALPPVM 100
    KQQPVAISSA PAFGMGGIAS MPPLTAVAPV PMGSIPVVGM SPTLVSSVPT 150
    AAVPPLANGA PPVIQPLPAF AHPAATLPKS SSFSRSGPGS QLNTKLQKAQ 200
    SFDVASVPPV AEWAVPQSSR LKYRQLFNSH DKTMSGHLTG PQARTILMQS 250
    SLPQAQLASI WNLSDIDQDG KLTAEEFILA MHLIDVAMSG QPLPPVLPPE 300
    YIPPSFRRVR SGSGISVISS TSVDQRLPEE PVLEDEQQQL EKKLPVTFED 350
    KKRENFERGN LELEKRRQAL LEQQRKEQER LAQLERAEQE RKERERQEQE 400
    RKRQLELEKQ LEKQRELERQ REEERRKEIE RREAAKRELE RQRQLEWERN 450
    RRQELLNQRN KEQEDIVVLK AKKKTLEFEL EALNDKKHQL EGKLQDIRCR 500
    LTTQRQEIES TNKSRELRIA EITHLQQQLQ ESQQMLGRLI PEKQILNDQL 550
    KQVQQNSLHR DSLVTLKRAL EAKELARQHL RDQLDEVEKE TRSKLQEIDI 600
    FNNQLKELRE IHNKQQLQKQ KSMEAERLKQ KEQERKIIEL EKQKEEAQRR 650
    AQERDKQWLE HVQQEDEHQR PRKLHEEEKL KREESVKKKD GEEKGKQEAQ 700
    DKLGRLFHQH QEPAKPAVQA PWSTAEKGPL TISAQENVKV VYYRALYPFE 750
    SRSHDEITIQ PGDIVMVDES QTGEPGWLGG ELKGKTGWFP ANYAEKIPEN 800
    EVPAPVKPVT DSTSAPAPKL ALRETPAPLA VTSSEPSTTP NNWADFSSTW 850
    PTSTNEKPET DNWDAWAAQP SLTVPSAGQL RQRSAFTPAT ATGSSPSPVL 900
    GQGEKVEGLQ AQALYPWRAK KDNHLNFNKN DVITVLEQQD MWWFGEVQGQ 950
    KGWFPKSYVK LISGPIRKST SMDSGSSESP ASLKRVASPA AKPVVSGEEF 1000
    IAMYTYESSE QGDLTFQQGD VILVTKKDGD WWTGTVGDKA GVFPSNYVRL 1050
    KDSEGSGTAG KTGSLGKKPG PSCNVK 1076
    Length:1,076
    Mass (Da):121,644
    Last modified:February 21, 2006 - v1
    Checksum:iFBFBD9081E1BE3BF
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ340865 mRNA. Translation: ABC69037.1.
    UniGeneiHs.160324.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ340865 mRNA. Translation: ABC69037.1 .
    UniGenei Hs.160324.

    3D structure databases

    ProteinModelPortali Q2LAE2.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q2LAE2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG052159.

    Gene expression databases

    Bgeei Q2LAE2.

    Family and domain databases

    Gene3Di 1.10.238.10. 2 hits.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF14604. SH3_9. 3 hits.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00054. EFh. 2 hits.
    SM00027. EH. 2 hits.
    SM00326. SH3. 3 hits.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 3 hits.
    PROSITEi PS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 2 hits.
    PS50031. EH. 2 hits.
    PS50002. SH3. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural diversity and differential expression of novel human intersectin 1 isoforms."
      Kropyvko S., Gerasymchuk D., Skrypkina I., Dergai M., Dergai O., Nikolaienko O., Rynditch A., Tsyba L.
      Mol. Biol. Rep. 37:2789-2796(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: KidneyImported.

    Entry informationi

    Entry nameiQ2LAE2_HUMAN
    AccessioniPrimary (citable) accession number: Q2LAE2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 21, 2006
    Last sequence update: February 21, 2006
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.