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Protein
Submitted name:

Intersectin 1 short form

Gene

ITSN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Intersectin 1 short formImported
Gene namesi
Name:ITSN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ2LAE2.

Expressioni

Gene expression databases

BgeeiQ2LAE2.

Structurei

3D structure databases

ProteinModelPortaliQ2LAE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG052159.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF14604. SH3_9. 3 hits.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 3 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 3 hits.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q2LAE2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
QFPTPFGGSL DIWAITVEER AKHDQQFHSL KPISGFITGD QARNFFFQSG
60 70 80 90 100
LPQPVLAQIW ALADMNNDGR MDQVEFSIAM KLIKLKLQGY QLPSALPPVM
110 120 130 140 150
KQQPVAISSA PAFGMGGIAS MPPLTAVAPV PMGSIPVVGM SPTLVSSVPT
160 170 180 190 200
AAVPPLANGA PPVIQPLPAF AHPAATLPKS SSFSRSGPGS QLNTKLQKAQ
210 220 230 240 250
SFDVASVPPV AEWAVPQSSR LKYRQLFNSH DKTMSGHLTG PQARTILMQS
260 270 280 290 300
SLPQAQLASI WNLSDIDQDG KLTAEEFILA MHLIDVAMSG QPLPPVLPPE
310 320 330 340 350
YIPPSFRRVR SGSGISVISS TSVDQRLPEE PVLEDEQQQL EKKLPVTFED
360 370 380 390 400
KKRENFERGN LELEKRRQAL LEQQRKEQER LAQLERAEQE RKERERQEQE
410 420 430 440 450
RKRQLELEKQ LEKQRELERQ REEERRKEIE RREAAKRELE RQRQLEWERN
460 470 480 490 500
RRQELLNQRN KEQEDIVVLK AKKKTLEFEL EALNDKKHQL EGKLQDIRCR
510 520 530 540 550
LTTQRQEIES TNKSRELRIA EITHLQQQLQ ESQQMLGRLI PEKQILNDQL
560 570 580 590 600
KQVQQNSLHR DSLVTLKRAL EAKELARQHL RDQLDEVEKE TRSKLQEIDI
610 620 630 640 650
FNNQLKELRE IHNKQQLQKQ KSMEAERLKQ KEQERKIIEL EKQKEEAQRR
660 670 680 690 700
AQERDKQWLE HVQQEDEHQR PRKLHEEEKL KREESVKKKD GEEKGKQEAQ
710 720 730 740 750
DKLGRLFHQH QEPAKPAVQA PWSTAEKGPL TISAQENVKV VYYRALYPFE
760 770 780 790 800
SRSHDEITIQ PGDIVMVDES QTGEPGWLGG ELKGKTGWFP ANYAEKIPEN
810 820 830 840 850
EVPAPVKPVT DSTSAPAPKL ALRETPAPLA VTSSEPSTTP NNWADFSSTW
860 870 880 890 900
PTSTNEKPET DNWDAWAAQP SLTVPSAGQL RQRSAFTPAT ATGSSPSPVL
910 920 930 940 950
GQGEKVEGLQ AQALYPWRAK KDNHLNFNKN DVITVLEQQD MWWFGEVQGQ
960 970 980 990 1000
KGWFPKSYVK LISGPIRKST SMDSGSSESP ASLKRVASPA AKPVVSGEEF
1010 1020 1030 1040 1050
IAMYTYESSE QGDLTFQQGD VILVTKKDGD WWTGTVGDKA GVFPSNYVRL
1060 1070
KDSEGSGTAG KTGSLGKKPG PSCNVK
Length:1,076
Mass (Da):121,644
Last modified:February 21, 2006 - v1
Checksum:iFBFBD9081E1BE3BF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ340865 mRNA. Translation: ABC69037.1.
UniGeneiHs.160324.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ340865 mRNA. Translation: ABC69037.1.
UniGeneiHs.160324.

3D structure databases

ProteinModelPortaliQ2LAE2.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ2LAE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG052159.

Gene expression databases

BgeeiQ2LAE2.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF14604. SH3_9. 3 hits.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 3 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 3 hits.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Structural diversity and differential expression of novel human intersectin 1 isoforms."
    Kropyvko S., Gerasymchuk D., Skrypkina I., Dergai M., Dergai O., Nikolaienko O., Rynditch A., Tsyba L.
    Mol. Biol. Rep. 37:2789-2796(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ2LAE2_HUMAN
AccessioniPrimary (citable) accession number: Q2LAE2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 21, 2006
Last sequence update: February 21, 2006
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.