Unreviewed, UniProtKB/TrEMBL Q2L6J2 (Q2L6J2_HUMAN)

Names and origin

Protein names

Recommended name:
    DNA-directed RNA polymerase subunit RuleBase RU004351V0

Gene names

Name:	ZNRD1 EMBL BAE78600.1
ORF Names:	DAAP-65D20.6-001 EMBL CAQ09120.1, DADB-60O11.10-001 EMBL CAQ06749.1, DAMA-377D17.11-001 EMBL CAQ10492.1, DAMC-182C13.9-001 EMBL CAQ08159.1, hCG_23775 EMBL EAX03250.1

Organism

Homo sapiens (Human) EMBL BAE78600.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	126 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. RuleBase RU003474V0

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase RuleBase RU003474V0
Domain	Zinc-finger RuleBase RU004353V0
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Biological process	regulation of transcription Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: InterPro transcription regulator activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2L6J2-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: C678AC7132A91432	FASTA	126	13,904
	10 20 30 40 50 60 MSVMDLANTC SSFQSDLDFC SDCGSVLPLP GAQDTVTCIR CGFNINVRDF EGKVVKTSVV 70 80 90 100 110 120 FHQLGTAMPM SVEEGPECQG PVVDRRCPRC GHEGMAYHTR QMRSADEGQT VFYTCTNCKF QEKEDS

References

[1]	"Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity." Shiina T., Ota M., Shimizu S., Katsuyama Y., Hashimoto N., Takasu M., Anzai T., Kulski J.K., Kikkawa E., Naruse T., Kimura N., Yanagiya K., Watanabe A., Hosomichi K., Kohara S., Iwamoto C., Umehara Y., Meyer A. , Wanner V., Sano K., Macquin C., Ikeo K., Tokunaga K., Gojobori T., Inoko H., Bahram S. Genetics 173:1555-1570(2006) [PubMed: 16702430] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Peripheral blood leukocyte EMBL BAE78600.1.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Wood J. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Griffiths C. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[5]	Brown J. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB202082 Genomic DNA. Translation: BAE78600.1. CR388205 Genomic DNA. Translation: CAQ06749.1. CR759763 Genomic DNA. Translation: CAQ08159.1. CR759960 Genomic DNA. Translation: CAQ09120.1. BX927229 Genomic DNA. Translation: CAQ10492.1. CH471081 Genomic DNA. Translation: EAX03250.1.
RefSeq	NP_055411.1. NP_740753.1.
UniGene	Hs.57813
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000066379. Homo sapiens. [Contig view] ENSG00000206429. Homo sapiens. [Contig view] ENSG00000206502. Homo sapiens. [Contig view]
GeneID	30834.
KEGG	hsa:30834.
Organism-specific databases
HGNC	HGNC:13182. ZNRD1.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q2L6J2.
Gene expression databases
ArrayExpress	Q2L6J2.
Family and domain databases
InterPro	IPR001529. DNA-dir_RNA_pol_M/15kDsu. IPR001222. Znf_TFIIS. [Graphical view]
Pfam	PF01096. TFIIS_C. 1 hit. [Graphical view]
SMART	SM00440. ZnF_C2C2. 1 hit. [Graphical view]
PROSITE	PS01030. RNA_POL_M_15KD. 1 hit. PS00466. ZF_TFIIS_1. 1 hit. PS51133. ZF_TFIIS_2. 1 hit. [Graphical view]
Other Resources
NextBio	52944.

Entry information

Entry name

Q2L6J2_HUMAN

Accession

Primary (citable) accession number: Q2L6J2

Entry history

Integrated into UniProtKB/TrEMBL:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	November 4, 2008
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)