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Protein
Submitted name:

Tripartite motif-containing 31

Gene

TRIM31

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Tripartite motif-containing 31Imported
Submitted name:
cDNA FLJ75322, highly similar to Homo sapiens tripartite motif-containing 31, transcript variant 1, mRNAImported
Gene namesi
Name:TRIM31Imported
ORF Names:DASS-211F20.2-001Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38117.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000365924.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 5742RING-typeInterPro annotationAdd
BLAST
Domaini90 – 13142B box-typeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains RING-type zinc finger.SAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2177. Eukaryota.
ENOG4111G04. LUCA.
HOVERGENiHBG083771.
KOiK12011.
OMAiYFCEQDG.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
4.10.45.10. 1 hit.
InterProiIPR000315. Znf_B-box.
IPR020457. Znf_B-box_chordata.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PfamiPF00643. zf-B_box. 1 hit.
[Graphical view]
PRINTSiPR01406. BBOXZNFINGER.
SMARTiSM00336. BBOX. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
PROSITEiPS50119. ZF_BBOX. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2L6J1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGQFVNKL QEEVICPICL DILQKPVTID CGHNFCLKCI TQIGETSCGF
60 70 80 90 100
FKCPLCKTSV RKNAIRFNSL LRNLVEKIQA LQASEVQSKR KEATCPRHQE
110 120 130 140 150
MFHYFCEDDG KFLCFVCRES KDHKSHNVSL IEEAAQNYQG QIQEQIQVLQ
160 170 180 190 200
QKEKETVQVK AQGVHRVDVF TDQVEHEKQR ILTEFELLHQ VLEEEKNFLL
210 220 230 240 250
SRIYWLGHEG TEAGKHYVAS TEPQLNDLKK LVDSLKTKQN MPPRQLLEDI
260 270 280 290 300
KVVLCRSEEF QFLNPTPVPL ELEKKLSEAK SRHDSITGSL KKFKDQLQAD
310 320 330 340 350
RKKDENRFFK SMNKNDMKSW GLLQKNNHKM NKTSEPGSSS AGGRTTSGPP
360 370 380 390 400
NHHSSAPSHS LFRASSAGKV TFPVCLLASY DEISGQGASS QDTKTFDVAL
410 420
SEELHAALSE WLTAIRAWFC EVPSS
Length:425
Mass (Da):48,244
Last modified:March 7, 2006 - v1
Checksum:i8CCC0D07F2DBB52D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB202083 Genomic DNA. Translation: BAE78603.1.
AK290270 mRNA. Translation: BAF82959.1.
BX897730, BX005441, BX088647 Genomic DNA. Translation: CAM26290.1.
RefSeqiNP_008959.3. NM_007028.4.
UniGeneiHs.493275.

Genome annotation databases

GeneIDi11074.
KEGGihsa:11074.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB202083 Genomic DNA. Translation: BAE78603.1.
AK290270 mRNA. Translation: BAF82959.1.
BX897730, BX005441, BX088647 Genomic DNA. Translation: CAM26290.1.
RefSeqiNP_008959.3. NM_007028.4.
UniGeneiHs.493275.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000365924.

Protocols and materials databases

DNASUi11074.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11074.
KEGGihsa:11074.

Organism-specific databases

CTDi11074.
PharmGKBiPA38117.

Phylogenomic databases

eggNOGiKOG2177. Eukaryota.
ENOG4111G04. LUCA.
HOVERGENiHBG083771.
KOiK12011.
OMAiYFCEQDG.

Miscellaneous databases

GenomeRNAii11074.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
4.10.45.10. 1 hit.
InterProiIPR000315. Znf_B-box.
IPR020457. Znf_B-box_chordata.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PfamiPF00643. zf-B_box. 1 hit.
[Graphical view]
PRINTSiPR01406. BBOXZNFINGER.
SMARTiSM00336. BBOX. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
PROSITEiPS50119. ZF_BBOX. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity."
    Shiina T., Ota M., Shimizu S., Katsuyama Y., Hashimoto N., Takasu M., Anzai T., Kulski J.K., Kikkawa E., Naruse T., Kimura N., Yanagiya K., Watanabe A., Hosomichi K., Kohara S., Iwamoto C., Umehara Y., Meyer A.
    , Wanner V., Sano K., Macquin C., Ikeo K., Tokunaga K., Gojobori T., Inoko H., Bahram S.
    Genetics 173:1555-1570(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Peripheral blood leukocyteImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ColonImported.
  3. Palmer S.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ2L6J1_HUMAN
AccessioniPrimary (citable) accession number: Q2L6J1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: June 8, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.