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Q2L4X1

- BZW2_MUSMM

UniProt

Q2L4X1 - BZW2_MUSMM

Protein

Basic leucine zipper and W2 domain-containing protein 2

Gene

Bzw2

Organism
Mus musculus molossinus (Japanese house mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
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    Functioni

    May be involved in neuronal differentiation.By similarity

    GO - Biological processi

    1. cell differentiation Source: UniProtKB-KW
    2. nervous system development Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Differentiation, Neurogenesis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Basic leucine zipper and W2 domain-containing protein 2
    Alternative name(s):
    Brain development-related molecule 2
    Gene namesi
    Name:Bzw2
    Synonyms:Bdm2
    OrganismiMus musculus molossinus (Japanese house mouse)
    Taxonomic identifieri57486 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1914162. Bzw2.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 419419Basic leucine zipper and W2 domain-containing protein 2PRO_0000254621Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei117 – 1171N6-acetyllysineBy similarity
    Modified residuei412 – 4121PhosphoserineBy similarity
    Modified residuei414 – 4141PhosphoserineBy similarity

    Keywords - PTMi

    Acetylation, Phosphoprotein

    PTM databases

    PhosphoSiteiQ2L4X1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2L4X1.
    SMRiQ2L4X1. Positions 256-406.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini248 – 415168W2PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the BZW family.Curated
    Contains 1 W2 domain.PROSITE-ProRule annotation

    Phylogenomic databases

    HOVERGENiHBG080940.

    Family and domain databases

    Gene3Di1.25.40.180. 1 hit.
    InterProiIPR016024. ARM-type_fold.
    IPR016021. MIF4-like_typ_1/2/3.
    IPR003307. W2_domain.
    [Graphical view]
    PfamiPF02020. W2. 1 hit.
    [Graphical view]
    SMARTiSM00515. eIF5C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.
    PROSITEiPS51363. W2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2L4X1-1 [UniParc]FASTAAdd to Basket

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    MNKHQKPVLT GQRFKTRKRD EKEKFEPTVF RDTLVQGLNE AGDDLEAVAK    50
    FLDSTGSRLD YRRYADTLFD ILVAGSMLAP GGTRIDDGDK TKMTNHCVFS 100
    ANEDHETIRN YAQVFNKLIR RYKYLEKAFE DEMKKLLLFL KAFSEAEQTK 150
    LAMLSGILLG NGTLPATILT SLFTDSLVKE GIAASFAVKL FKAWMAEKDA 200
    NSVTSSLRKA NLDKRLLELF PVNRQSVDHF AKYFTDAGLK ELSDFLRVQQ 250
    SLGTRKELQK ELQERLSQEC PIKEVVLYVK EEMKRNDLPE TAVIGLLWTC 300
    IMNAVEWNKK EELVAEQALK HLKQYAPLLA VFSSQGQSEL VLLQKVQEYC 350
    YDNIHFMKAF QKIVVLFYKA DVLSEEAILK WYKEAHAAKG KSVFLDQMKK 400
    FVEWLQNAEE ESESEGEES 419
    Length:419
    Mass (Da):48,063
    Last modified:March 7, 2006 - v1
    Checksum:i996FC462B50EAF6F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB244988 mRNA. Translation: BAE79268.1.
    CCDSiCCDS25884.1.
    UniGeneiMm.288669.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB244988 mRNA. Translation: BAE79268.1 .
    CCDSi CCDS25884.1.
    UniGenei Mm.288669.

    3D structure databases

    ProteinModelPortali Q2L4X1.
    SMRi Q2L4X1. Positions 256-406.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q2L4X1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1914162. Bzw2.

    Phylogenomic databases

    HOVERGENi HBG080940.

    Family and domain databases

    Gene3Di 1.25.40.180. 1 hit.
    InterProi IPR016024. ARM-type_fold.
    IPR016021. MIF4-like_typ_1/2/3.
    IPR003307. W2_domain.
    [Graphical view ]
    Pfami PF02020. W2. 1 hit.
    [Graphical view ]
    SMARTi SM00515. eIF5C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    PROSITEi PS51363. W2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and characterization of murine cDNA clones using newly constructed gene trap vector."
      Tashiro H., Moriguchi A., Noguchi M., Shirasaki R., Yoshida N., Shirafuji N.
      Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiBZW2_MUSMM
    AccessioniPrimary (citable) accession number: Q2L4X1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3