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Q2L4X1 (BZW2_MUSMM) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Basic leucine zipper and W2 domain-containing protein 2
Alternative name(s):
Brain development-related molecule 2
Gene names
Name:Bzw2
Synonyms:Bdm2
OrganismMus musculus molossinus (Japanese house mouse)
Taxonomic identifier57486 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in neuronal differentiation By similarity.

Sequence similarities

Belongs to the BZW family.

Contains 1 W2 domain.

Ontologies

Keywords
   Biological processDifferentiation
Neurogenesis
   Molecular functionDevelopmental protein
   PTMAcetylation
Phosphoprotein
Gene Ontology (GO)
   Biological_processcell differentiation

Inferred from electronic annotation. Source: UniProtKB-KW

nervous system development

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 419419Basic leucine zipper and W2 domain-containing protein 2
PRO_0000254621

Regions

Domain248 – 415168W2

Amino acid modifications

Modified residue1171N6-acetyllysine By similarity
Modified residue4121Phosphoserine By similarity
Modified residue4141Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2L4X1 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 996FC462B50EAF6F

FASTA41948,063
        10         20         30         40         50         60 
MNKHQKPVLT GQRFKTRKRD EKEKFEPTVF RDTLVQGLNE AGDDLEAVAK FLDSTGSRLD 

        70         80         90        100        110        120 
YRRYADTLFD ILVAGSMLAP GGTRIDDGDK TKMTNHCVFS ANEDHETIRN YAQVFNKLIR 

       130        140        150        160        170        180 
RYKYLEKAFE DEMKKLLLFL KAFSEAEQTK LAMLSGILLG NGTLPATILT SLFTDSLVKE 

       190        200        210        220        230        240 
GIAASFAVKL FKAWMAEKDA NSVTSSLRKA NLDKRLLELF PVNRQSVDHF AKYFTDAGLK 

       250        260        270        280        290        300 
ELSDFLRVQQ SLGTRKELQK ELQERLSQEC PIKEVVLYVK EEMKRNDLPE TAVIGLLWTC 

       310        320        330        340        350        360 
IMNAVEWNKK EELVAEQALK HLKQYAPLLA VFSSQGQSEL VLLQKVQEYC YDNIHFMKAF 

       370        380        390        400        410 
QKIVVLFYKA DVLSEEAILK WYKEAHAAKG KSVFLDQMKK FVEWLQNAEE ESESEGEES 

« Hide

References

[1]"Isolation and characterization of murine cDNA clones using newly constructed gene trap vector."
Tashiro H., Moriguchi A., Noguchi M., Shirasaki R., Yoshida N., Shirafuji N.
Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB244988 mRNA. Translation: BAE79268.1.
UniGeneMm.288669.

3D structure databases

ProteinModelPortalQ2L4X1.
SMRQ2L4X1. Positions 256-406.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ2L4X1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:1914162. Bzw2.

Phylogenomic databases

HOVERGENHBG080940.

Family and domain databases

Gene3D1.25.40.180. 1 hit.
InterProIPR016024. ARM-type_fold.
IPR016021. MIF4-like_typ_1/2/3.
IPR003307. W2_domain.
[Graphical view]
PfamPF02020. W2. 1 hit.
[Graphical view]
SMARTSM00515. eIF5C. 1 hit.
[Graphical view]
SUPFAMSSF48371. SSF48371. 1 hit.
PROSITEPS51363. W2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBZW2_MUSMM
AccessionPrimary (citable) accession number: Q2L4X1
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 7, 2006
Last modified: December 11, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot