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Q2L4X1

- BZW2_MUSMM

UniProt

Q2L4X1 - BZW2_MUSMM

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Protein

Basic leucine zipper and W2 domain-containing protein 2

Gene

Bzw2

Organism
Mus musculus molossinus (Japanese house mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

May be involved in neuronal differentiation.By similarity

GO - Biological processi

  1. cell differentiation Source: UniProtKB-KW
  2. nervous system development Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Differentiation, Neurogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Basic leucine zipper and W2 domain-containing protein 2
Alternative name(s):
Brain development-related molecule 2
Gene namesi
Name:Bzw2
Synonyms:Bdm2
OrganismiMus musculus molossinus (Japanese house mouse)
Taxonomic identifieri57486 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1914162. Bzw2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 419419Basic leucine zipper and W2 domain-containing protein 2PRO_0000254621Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei117 – 1171N6-acetyllysineBy similarity
Modified residuei412 – 4121PhosphoserineBy similarity
Modified residuei414 – 4141PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

PTM databases

PhosphoSiteiQ2L4X1.

Structurei

3D structure databases

ProteinModelPortaliQ2L4X1.
SMRiQ2L4X1. Positions 256-406.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini248 – 415168W2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the BZW family.Curated
Contains 1 W2 domain.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG080940.

Family and domain databases

Gene3Di1.25.40.180. 1 hit.
InterProiIPR016024. ARM-type_fold.
IPR016021. MIF4-like_typ_1/2/3.
IPR003307. W2_domain.
[Graphical view]
PfamiPF02020. W2. 1 hit.
[Graphical view]
SMARTiSM00515. eIF5C. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS51363. W2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2L4X1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNKHQKPVLT GQRFKTRKRD EKEKFEPTVF RDTLVQGLNE AGDDLEAVAK
60 70 80 90 100
FLDSTGSRLD YRRYADTLFD ILVAGSMLAP GGTRIDDGDK TKMTNHCVFS
110 120 130 140 150
ANEDHETIRN YAQVFNKLIR RYKYLEKAFE DEMKKLLLFL KAFSEAEQTK
160 170 180 190 200
LAMLSGILLG NGTLPATILT SLFTDSLVKE GIAASFAVKL FKAWMAEKDA
210 220 230 240 250
NSVTSSLRKA NLDKRLLELF PVNRQSVDHF AKYFTDAGLK ELSDFLRVQQ
260 270 280 290 300
SLGTRKELQK ELQERLSQEC PIKEVVLYVK EEMKRNDLPE TAVIGLLWTC
310 320 330 340 350
IMNAVEWNKK EELVAEQALK HLKQYAPLLA VFSSQGQSEL VLLQKVQEYC
360 370 380 390 400
YDNIHFMKAF QKIVVLFYKA DVLSEEAILK WYKEAHAAKG KSVFLDQMKK
410
FVEWLQNAEE ESESEGEES
Length:419
Mass (Da):48,063
Last modified:March 7, 2006 - v1
Checksum:i996FC462B50EAF6F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB244988 mRNA. Translation: BAE79268.1.
CCDSiCCDS25884.1.
UniGeneiMm.288669.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB244988 mRNA. Translation: BAE79268.1 .
CCDSi CCDS25884.1.
UniGenei Mm.288669.

3D structure databases

ProteinModelPortali Q2L4X1.
SMRi Q2L4X1. Positions 256-406.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q2L4X1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1914162. Bzw2.

Phylogenomic databases

HOVERGENi HBG080940.

Family and domain databases

Gene3Di 1.25.40.180. 1 hit.
InterProi IPR016024. ARM-type_fold.
IPR016021. MIF4-like_typ_1/2/3.
IPR003307. W2_domain.
[Graphical view ]
Pfami PF02020. W2. 1 hit.
[Graphical view ]
SMARTi SM00515. eIF5C. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
PROSITEi PS51363. W2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Isolation and characterization of murine cDNA clones using newly constructed gene trap vector."
    Tashiro H., Moriguchi A., Noguchi M., Shirasaki R., Yoshida N., Shirafuji N.
    Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiBZW2_MUSMM
AccessioniPrimary (citable) accession number: Q2L4X1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 7, 2006
Last modified: October 1, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3