ID   UBIC_BORA1              Reviewed;         198 AA.
AC   Q2L1H6;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Probable chorismate--pyruvate lyase;
DE            Short=CL;
DE            Short=CPL;
DE            EC=4.1.3.40;
GN   Name=ubiC; OrderedLocusNames=BAV1650;
OS   Bordetella avium (strain 197N).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=360910;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16885469; DOI=10.1128/JB.01927-05;
RA   Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D.,
RA   King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D.,
RA   Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R.,
RA   Squares S., Woodward J., Parkhill J., Temple L.M.;
RT   "Comparison of the genome sequence of the poultry pathogen Bordetella
RT   avium with those of B. bronchiseptica, B. pertussis, and B.
RT   parapertussis reveals extensive diversity in surface structures
RT   associated with host interaction.";
RL   J. Bacteriol. 188:6002-6015(2006).
CC   -!- FUNCTION: Removes the pyruvyl group from chorismate, with
CC       concomitant aromatization of the ring, to provide 4-
CC       hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity).
CC   -!- CATALYTIC ACTIVITY: Chorismate = 4-hydroxybenzoate + pyruvate.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the ubiC family.
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DR   EMBL; AM167904; CAJ49258.1; -; Genomic_DNA.
DR   RefSeq; YP_786168.1; -.
DR   GeneID; 6265545; -.
DR   GenomeReviews; AM167904_GR; BAV1650.
DR   KEGG; bav:BAV1650; -.
DR   NMPDR; fig|521.1.peg.1761; -.
DR   HOGENOM; Q2L1H6; -.
DR   OMA; Q2L1H6; SAIWARR.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008813; F:chorismate lyase activity; IEA:HAMAP.
DR   GO; GO:0042866; P:pyruvate biosynthetic process; IEA:HAMAP.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_01632; -; 1.
DR   InterPro; IPR007440; Chorismate_lyase.
DR   Pfam; PF04345; Chor_lyase; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Lyase; Pyruvate;
KW   Ubiquinone biosynthesis.
FT   CHAIN         1    198       Probable chorismate--pyruvate lyase.
FT                                /FTId=PRO_0000240536.
FT   BINDING      76     76       Substrate (By similarity).
FT   BINDING     114    114       Substrate; via amide nitrogen (By
FT                                similarity).
SQ   SEQUENCE   198 AA;  22167 MW;  5FF2943BEB5D1272 CRC64;
     MTTKYQAPLA AGWLIRAPSL LSPTQRHWLF RPGALTAGLR QLGKVQLRVV SEHAEGASLD
     EARAMLIAPG SPVWVREVLM SVDGIDSVPA RSLTPLAASH GSWQGMRRLL TRPLADMLYH
     DRGVTRSPFV CRRLSSPLPF YRMALPPNHD GSAIWARRSV FWRHGQPLLV AECFLPDFWR
     KVTLGRAIPP LKAHDRRA
//