Reviewed, UniProtKB/Swiss-Prot Q2L1H6 (UBIC_BORA1)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	BAV1650

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 198	198	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000240536
Sites
	Binding site	76	1	Substrate By similarity
	Binding site	114	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2L1H6-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 5FF2943BEB5D1272	FASTA	198	22,167
	10 20 30 40 50 60 MTTKYQAPLA AGWLIRAPSL LSPTQRHWLF RPGALTAGLR QLGKVQLRVV SEHAEGASLD 70 80 90 100 110 120 EARAMLIAPG SPVWVREVLM SVDGIDSVPA RSLTPLAASH GSWQGMRRLL TRPLADMLYH 130 140 150 160 170 180 DRGVTRSPFV CRRLSSPLPF YRMALPPNHD GSAIWARRSV FWRHGQPLLV AECFLPDFWR 190 KVTLGRAIPP LKAHDRRA

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM167904 Genomic DNA. Translation: CAJ49258.1.
RefSeq	YP_786168.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6265545.
GenomeReviews	Gene locus BAV1650 in contig AM167904_GR.
KEGG	bav:BAV1650.
NMPDR	fig|521.1.peg.1761.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2L1H6.
OMA	Q2L1H6. SAIWARR.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_BORA1

Accession

Primary (citable) accession number: Q2L1H6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	March 7, 2006
Last modified:	June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)