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Q2L0K8 (PSD_BORA1) Reviewed, UniProtKB/Swiss-Prot

Last modified August 10, 2010. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
Customize displayNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:BAV1882
OrganismBordetella avium (strain 197N) [Complete proteome] [HAMAP]
Taxonomic identifier360910 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length294 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 251251Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000262097
Chain252 – 29443Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000262098

Sites

Site251 – 2522Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2521Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2L0K8-1 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: E393DB6CA26826A2

FASTA29432,211
        10         20         30         40         50         60 
MSIKDQIFLA SQHLAPHHLV SRGMGLLADS RIPALKNAMI SRFVQRYNVD MSEALVEDPL 

        70         80         90        100        110        120 
AYPCFNDFFT RALKPDARPL DDDSANVLSP ADGTISQLGP IREGRIFQAK GHSFGLTALL 

       130        140        150        160        170        180 
GGDAERAAPF EGGDFATIYL SPRDYHRVHM PVTGTLREMV HVPGRLFSVN PLTANTVPDL 

       190        200        210        220        230        240 
FARNERVVCI FDTAYGPMAV ILVGAMIVAS VETVWAGLVT PHKREVRSTR YGPQEPIVLE 

       250        260        270        280        290 
RGAEMGRFKL GSTAIVLFGP GRIRWFDTPS VRGPIRMGET LALPANHLED VPAV

« Hide

References

[1]"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction."
Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M.
J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM167904 Genomic DNA. Translation: CAJ49491.1.
RefSeqYP_786399.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6265669.
GenomeReviewsGene locus BAV1882 in contig AM167904_GR.
KEGGbav:BAV1882.
NMPDRfig|521.1.peg.1597.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG302256.
OMAMATVWHG.
ProtClustDBPRK00044.

Enzyme and pathway databases

BioCycABAU360910:BAV1882-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_BORA1
AccessionPrimary (citable) accession number: Q2L0K8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 7, 2006
Last modified: August 10, 2010
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents