Q2L0A6 (GPMA_BORA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Short name=BPG-dependent PGAM
Short name=PGAM
Short name=Phosphoglyceromutase
Short name=dPGM
EC=5.4.2.1

Gene names

Name:	gpmA
Ordered Locus Names:	BAV0243

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	250 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01039
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 250	250	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HAMAP MF_01039		PRO_1000064032
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity
	Active site	182	1	By similarity
	Site	60	1	Interaction with carboxyl group of phosphoglycerates By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2L0A6 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: B316A962F1CE1A32	FASTA	250	28,377
	10 20 30 40 50 60 MYKLVLMRHG ESQWNLENRF TGWTDVDLTE VGREQARRAG ELLKREGYTF DLAYASVLKR 70 80 90 100 110 120 AIRTLWIALD AMDAMYTPVG LNWRLNERHY GQLQGLNKAE TAAKYGDEQV LIWRRAYAIA 130 140 150 160 170 180 PEPLDIDDPR HPRFDSRYAK IPAEQLPATE CLRDTVARVL PFWNESIAPA IRAGRRVLVA 190 200 210 220 230 240 AHGNSLRALI KHLDNISDDA IVELNIPTGQ PLVYELDENL RPIRHYYLGD AAEIEAAMAA 250 VAAQGKAKKD

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 197N.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM167904 Genomic DNA. Translation: CAJ47848.1.
RefSeq	YP_784781.1. NC_010645.1.
3D structure databases
ProteinModelPortal	Q2L0A6.
SMR	Q2L0A6. Positions 3-239.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2L0A6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6264588.
GenomeReviews	Gene locus BAV0243 in contig AM167904_GR.
KEGG	bav:BAV0243.
NMPDR	fig|521.1.peg.2638.
PATRIC	21126630. VBIBorAvi43433_0256.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG658938.
OMA	EWNALNL.
ProtClustDB	PRK14115.
Enzyme and pathway databases
BioCyc	ABAU360910:BAV0243-MONOMER.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA. [Tree]
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
KO	K01834.
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. Pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GPMA_BORA1

Accession

Primary (citable) accession number: Q2L0A6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program