ID   ADC_BORA1               Reviewed;         246 AA.
AC   Q2L048;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 18.
DE   RecName: Full=Probable acetoacetate decarboxylase;
DE            Short=ADC;
DE            Short=AAD;
DE            EC=4.1.1.4;
GN   Name=adc; OrderedLocusNames=BAV0264;
OS   Bordetella avium (strain 197N).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=360910;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16885469; DOI=10.1128/JB.01927-05;
RA   Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D.,
RA   King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D.,
RA   Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R.,
RA   Squares S., Woodward J., Parkhill J., Temple L.M.;
RT   "Comparison of the genome sequence of the poultry pathogen Bordetella
RT   avium with those of B. bronchiseptica, B. pertussis, and B.
RT   parapertussis reveals extensive diversity in surface structures
RT   associated with host interaction.";
RL   J. Bacteriol. 188:6002-6015(2006).
CC   -!- FUNCTION: Catalyzes the conversion of acetoacetate to acetone and
CC       carbon dioxide (By similarity).
CC   -!- CATALYTIC ACTIVITY: Acetoacetate = acetone + CO(2).
CC   -!- SIMILARITY: Belongs to the ADC family.
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DR   EMBL; AM167904; CAJ47869.1; -; Genomic_DNA.
DR   RefSeq; YP_784802.1; -.
DR   GeneID; 6266695; -.
DR   GenomeReviews; AM167904_GR; BAV0264.
DR   KEGG; bav:BAV0264; -.
DR   NMPDR; fig|521.1.peg.2632; -.
DR   HOGENOM; Q2L048; -.
DR   OMA; Q2L048; TATMGYK.
DR   GO; GO:0047602; F:acetoacetate decarboxylase activity; IEA:HAMAP.
DR   HAMAP; MF_00597; -; 1.
DR   InterPro; IPR010451; Acetoacetate_decarboxylase.
DR   Pfam; PF06314; ADC; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Decarboxylase; Lyase; Schiff base.
FT   CHAIN         1    246       Probable acetoacetate decarboxylase.
FT                                /FTId=PRO_1000025630.
FT   ACT_SITE    116    116       Schiff-base intermediate with
FT                                acetoacetate (By similarity).
SQ   SEQUENCE   246 AA;  27282 MW;  89E44F015E68CCDC CRC64;
     MNIDTVRANA FAMPLTSPAF PMGPYRFVKR EFFVITYRTD PEALRSVVPE PLAVTQPLVH
     YEFIRMPDST GFGDYTESGQ VIPVEYEGVA GSYTHAMYLN DHPPIAGGRE LWGFPKKLAL
     PTLKVHTDTL VGTLDYGPIR VATGTMGYKH EEVDIVEQAR HLSAPNFLLK IIPHVDCSPR
     ICELVRYYLE DIRVYGAWSG PAALELAPHA LAPVADLPVL EVVGARHFIA DLTLGLGEVV
     YDYLAK
//