Reviewed, UniProtKB/Swiss-Prot Q2KYR0 (DCD_BORA1)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	BAV0477

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 187	187	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009683

Sequences

	Sequence		Length	Mass (Da)
	Q2KYR0-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: DAA632BDDA76DB47	FASTA	187	20,803
	10 20 30 40 50 60 MSIKSDRWIR RAAEGGMIEP FEAGQVRTVN GGRIVSYGTS SYGYDVRCAD EFKIFTNINS 70 80 90 100 110 120 TIVDPKNFDE GSFVDFKGDV CIIPPNSFAL ARTVEYFRIP RSVLTICLGK STYARCGIIV 130 140 150 160 170 180 NVTPLEPEWE GHVTLEFSNT TPLPAKIYAG EGCAQMLFLE SDEVCETSYR DRGGKYQGQR GVTLPRT

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM167904 Genomic DNA. Translation: CAJ48082.1.
RefSeq	YP_785010.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6264770.
GenomeReviews	Gene locus BAV0477 in contig AM167904_GR.
KEGG	bav:BAV0477.
NMPDR	fig|521.1.peg.1064.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2KYR0.
OMA	Q2KYR0. CAQVLFF.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_BORA1

Accession

Primary (citable) accession number: Q2KYR0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	March 7, 2006
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)