Reviewed, UniProtKB/Swiss-Prot Q2KYM1 (TRPF_BORA1)

Names and origin

Protein names

Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase
      Short name=PRAI
    EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	BAV2264

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	219 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP MF_00135
Sequence similarities	Belongs to the trpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 219	219	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP MF_00135		PRO_1000076429

Sequences

	Sequence		Length	Mass (Da)
	Q2KYM1-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 91875D462EFCD270	FASTA	219	23,380
	10 20 30 40 50 60 MRTRVKICGL TREADIAQAI EAGVDAIGLI CYAGSKRYVD LARAARLRRE VPAFVSVVTL 70 80 90 100 110 120 FVNPAPDEVR AVLDHVGPDL LQFHGDESPE DCTRYGHRFM RAFRVGAAGL DSAGAIAAAC 130 140 150 160 170 180 RPYHEAAGWL FDSYSSGYGG SGLTFDHSLL AEVQADAGSR PLVLAGGLNP DNIAQALALV 190 200 210 QPWAVDVSSG VESGPGLKSA DKMKEFLKRI KKVDDDLHA

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM167904 Genomic DNA. Translation: CAJ49874.1.
RefSeq	YP_786778.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6267890.
GenomeReviews	Gene locus BAV2264 in contig AM167904_GR.
KEGG	bav:BAV2264.
NMPDR	fig|521.1.peg.161.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2KYM1.
OMA	Q2KYM1. SKICGIT.
Family and domain databases
HAMAP	MF_00135. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPF_BORA1

Accession

Primary (citable) accession number: Q2KYM1

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	March 7, 2006
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)