Q2KYK7 (AROC_BORA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Chorismate synthase
EC=4.2.3.5

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	BAV2273

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity. HAMAP MF_00300
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity. HAMAP MF_00300
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 352	352	Chorismate synthase HAMAP MF_00300		PRO_0000256274

Sequences

	Sequence		Length	Mass (Da)
	Q2KYK7 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 17A7839A45C84D75	FASTA	352	37,544
	10 20 30 40 50 60 MSGNTLGSLF RVTNFGESHG PAIGCVVDGC PPGLPLDAAD IQRELDRRRP GTSRHVTQRQ 70 80 90 100 110 120 EADQVEILSG VYEGVTTGTP IGLLIRNIDA RSKDYSNIAD TFRPGHADYS YWKKFGQRDP 130 140 150 160 170 180 RGGGRSSARL TAPTVAAGAI AKKWLAQQHG TIVRGYMSQL GPIEIPFVSW DEVPNNPFYA 190 200 210 220 230 240 PNAAIVPELE AYMDALRRDG DSIGARIEVV AEHLPAGWGE PIYDRLDADI AHAMMGLNAV 250 260 270 280 290 300 KGVSIGAGFG SITQRGSEHG DEITPDGFLS NHAGGVLGGI STGQPVTVSL AIKPTSSIRV 310 320 330 340 350 ERRSVNRAGE PVNVQTLGRH DPCVGIRATP IAEALLALVL IDHALRHRGQ CG

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 197N.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM167904 Genomic DNA. Translation: CAJ49883.1.
RefSeq	YP_786787.1. NC_010645.1.
3D structure databases
HSSP	HSSP built from PDB template 1ZTB based on UniProtKB P63611.
ProteinModelPortal	Q2KYK7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2KYK7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6265887.
GenomeReviews	Gene locus BAV2273 in contig AM167904_GR.
KEGG	bav:BAV2273.
NMPDR	fig|521.1.peg.152.
PATRIC	21130773. VBIBorAvi43433_2296.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG292336.
OMA	SRFTTQR.
ProtClustDB	PRK05382.
Enzyme and pathway databases
BioCyc	ABAU360910:BAV2273-MONOMER.
Family and domain databases
HAMAP	MF_00300. Chorismate_synth. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
KO	K01736.
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
SUPFAM	SSF103263. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. AroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_BORA1

Accession

Primary (citable) accession number: Q2KYK7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program