Reviewed, UniProtKB/Swiss-Prot Q2KYE9 (G6PI_BORA1)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	BAV0519

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	520 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 520	520	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_0000252610
Sites
	Active site	327	1	Proton donor By similarity
	Active site	358	1	By similarity
	Active site	486	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2KYE9-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 7695D4A3B9936D9A	FASTA	520	56,800
	10 20 30 40 50 60 MPQSLPFSPA WLAFEEAVRG ASHRGDHLRI IEGGGLSVDL TAQAYSPQLE AAGLALCEQQ 70 80 90 100 110 120 GFALARRQLF EGGEANWTEH RPAWHTALRA ALPPPSVAKD ILNERERLRR FVDEADARGA 130 140 150 160 170 180 YKYVLHLGIG GSDWGPRLVA RALRHQGLKR EVRFASNVDS HAVADAMHQL DPHETLVIVA 190 200 210 220 230 240 SKSFTTTEPL ANAEVAIHWL QNAGVADPIK QVVAITANVD AALDFGISPQ HVFRFWDWVG 250 260 270 280 290 300 GRYSLWSAIG LPIALAMGNN TFDELLAGAA AMDEHFLRAP LAANAPVQMA LAGLANRSVM 310 320 330 340 350 360 GFNSLAIAPY DSRLAHLVPW AQQLEMESLG KVATRDGSPA GVPTGPVVWG MTGTDCQHTF 370 380 390 400 410 420 FQWLHQDTTG APVDFIVCEH ADHTYDHHHR LLIANCLAQR AALLRGKSFE DALAETCARV 430 440 450 460 470 480 DDPSEARILA EHLVHPGRRP STLIVLPRMT AHNLGALLAL YEHKVFTQGV LWGINPFDQW 490 500 510 520 GVEFGKALAR GIIGELDKPS GMASADPSTR YWVDLLSRRS

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM167904 Genomic DNA. Translation: CAJ48124.1.
RefSeq	YP_785052.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6267932.
GenomeReviews	Gene locus BAV0519 in contig AM167904_GR.
KEGG	bav:BAV0519.
NMPDR	fig|521.1.peg.2329.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2KYE9.
OMA	Q2KYE9. LANSCEL.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_BORA1

Accession

Primary (citable) accession number: Q2KYE9

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	March 7, 2006
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)