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Q2KYE9 (G6PI_BORA1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:BAV0519
OrganismBordetella avium (strain 197N) [Complete proteome] [HAMAP]
Taxonomic identifier360910 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length520 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 520520Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252610

Sites

Active site3271Proton donor By similarity
Active site3581 By similarity
Active site4861 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2KYE9 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 7695D4A3B9936D9A

FASTA52056,800
        10         20         30         40         50         60 
MPQSLPFSPA WLAFEEAVRG ASHRGDHLRI IEGGGLSVDL TAQAYSPQLE AAGLALCEQQ 

        70         80         90        100        110        120 
GFALARRQLF EGGEANWTEH RPAWHTALRA ALPPPSVAKD ILNERERLRR FVDEADARGA 

       130        140        150        160        170        180 
YKYVLHLGIG GSDWGPRLVA RALRHQGLKR EVRFASNVDS HAVADAMHQL DPHETLVIVA 

       190        200        210        220        230        240 
SKSFTTTEPL ANAEVAIHWL QNAGVADPIK QVVAITANVD AALDFGISPQ HVFRFWDWVG 

       250        260        270        280        290        300 
GRYSLWSAIG LPIALAMGNN TFDELLAGAA AMDEHFLRAP LAANAPVQMA LAGLANRSVM 

       310        320        330        340        350        360 
GFNSLAIAPY DSRLAHLVPW AQQLEMESLG KVATRDGSPA GVPTGPVVWG MTGTDCQHTF 

       370        380        390        400        410        420 
FQWLHQDTTG APVDFIVCEH ADHTYDHHHR LLIANCLAQR AALLRGKSFE DALAETCARV 

       430        440        450        460        470        480 
DDPSEARILA EHLVHPGRRP STLIVLPRMT AHNLGALLAL YEHKVFTQGV LWGINPFDQW 

       490        500        510        520 
GVEFGKALAR GIIGELDKPS GMASADPSTR YWVDLLSRRS 

« Hide

References

[1]"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction."
Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M.
J. Bacteriol. 188:6002-6015(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 197N.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM167904 Genomic DNA. Translation: CAJ48124.1.
RefSeqYP_785052.1. NC_010645.1.

3D structure databases

ProteinModelPortalQ2KYE9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING360910.BAV0519.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6267932.
KEGGbav:BAV0519.
PATRIC21127190. VBIBorAvi43433_0531.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMARLKYFAA.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycBAVI360910:GCKI-529-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_BORA1
AccessionPrimary (citable) accession number: Q2KYE9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: March 7, 2006
Last modified: February 19, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways