Reviewed, UniProtKB/Swiss-Prot Q2KY92 (SYH_BORA1)

Names and origin

Protein names

Recommended name:
    Histidyl-tRNA synthetase
    EC=6.1.1.21
Alternative name(s):
    Histidine--tRNA ligase
      Short name=HisRS

Gene names

Name:	hisS
Ordered Locus Names:	BAV2343

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). HAMAP MF_00127
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP histidine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 428	428	Histidyl-tRNA synthetase HAMAP MF_00127		PRO_1000016315

Sequences

	Sequence		Length	Mass (Da)
	Q2KY92-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 914D6819BD979D53	FASTA	428	47,191
	10 20 30 40 50 60 MTQAFQKVSA IRGMNDVLPG PSAQWERFEE IVRAWLQGYG YRNVRTPILE QTRLFTRGIG 70 80 90 100 110 120 EVTDIVEKEM YTFTDALNGE SLTMRPEMTA GVVRAAIEHN MLYERPHRVY SIGPVFRHER 130 140 150 160 170 180 PQRGRYRQFH QIDVEALGFA GPDIDAELIV MLGRLWNTLG LADIRLELNS LGQPAERAAH 190 200 210 220 230 240 RAALIEYLEK HVDILDEDGK RRLYTNPLRV LDTKNPALQE MANAAPRLFD FLGEASRAHF 250 260 270 280 290 300 DGVCQRLDDA GIGYSLNPRL VRGLDYYNLT VFEWVTDRLG SQGTVCGGGR YDGLIELLGG 310 320 330 340 350 360 KPAPAVGFAI GVERLLDLWE QSAGQQTPPE CEVYVVHQGE GAQRLAARVG EDLRDAGLSV 370 380 390 400 410 420 IVHAGAASFK SQFKRADASG ARVAVILGDD EVATKTASVK YLRADAAGEG AQDKVALATL ASVLKSKG

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM167904 Genomic DNA. Translation: CAJ49953.1.
RefSeq	YP_786857.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6265925.
GenomeReviews	Gene locus BAV2343 in contig AM167904_GR.
KEGG	bav:BAV2343.
NMPDR	fig|521.1.peg.108.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2KY92.
OMA	Q2KY92. VFEWVTT.
Family and domain databases
HAMAP	MF_00127. [Tree]
InterPro	IPR002314. aa-tRNA-synt_IIb_cons-reg. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004154. Anticodon_bd. IPR015807. His-tRNA-synth_IIa_sub. IPR004516. His-tRNA_synth_IIA. [Graphical view]
Gene3D	G3DSA:3.40.50.800. Anticodon_bd. 1 hit.
PANTHER	PTHR11476. His-tRNA_synth. 1 hit.
Pfam	PF03129. HGTP_anticodon. 1 hit. PF00587. tRNA-synt_2b. 1 hit. [Graphical view]
PIRSF	PIRSF001549. His-tRNA_synth. 1 hit.
TIGRFAMs	TIGR00442. hisS. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYH_BORA1

Accession

Primary (citable) accession number: Q2KY92

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	March 7, 2006
Last modified:	June 16, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)