Q2KX12 (MQO_BORA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	BAV0729

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000325488

Sequences

	Sequence		Length	Mass (Da)
	Q2KX12 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 938733533BC458FF	FASTA	500	54,850
	10 20 30 40 50 60 MTTTSNLPEQ ADIVMIGAGI MSATLATVLK ALEPSLKIVM LETLNDCAME SSNGWNNAGT 70 80 90 100 110 120 GHAANCEMNY TPPRPDGTVD ISRALEVNTE FDLSRQLWSY LVKTGAIPDP QAFIHPCPHM 130 140 150 160 170 180 SMVWGADNVK YLRQRFKEMS AHHCYRGMEY SEDPKQIAEW VPLVMQGRSG NEPIAVTRIV 190 200 210 220 230 240 SGADVDYGAL THLLIKSLTE QAGFEVHYLK HVHDLARQRD GSWRIGIRDR GSKAQQTIQA 250 260 270 280 290 300 KFVFVGAGGG AIELLQKSGI PEGHGYGGFP VSGIWLRCDV DSMSERHHAK VYGKAPHGSP 310 320 330 340 350 360 PMSVPHLDTR IIGGKRSLLF GPYAGFSSRF LKHGSLTDLF RSVRPGNVLP MLDVAKDNWP 370 380 390 400 410 420 LTEYLVSQVL QSAGHQFEML RQYYPEARNH DWTHAVAGQR VQIIKPGTDK VGVLEFGTEL 430 440 450 460 470 480 VTSADRSFAA LLGASPGAST AAFIALEVLQ KCFADKLTAD AWLPRLKTVI PTYGVDLKTD 490 500 AEACFSIRKS TASVLNLDYV

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 197N.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM167904 Genomic DNA. Translation: CAJ48342.1.
RefSeq	YP_785262.1. NC_010645.1.
3D structure databases
ProteinModelPortal	Q2KX12.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2KX12.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6267556.
GenomeReviews	Gene locus BAV0729 in contig AM167904_GR.
KEGG	bav:BAV0729.
NMPDR	fig|521.1.peg.893.
PATRIC	21127622. VBIBorAvi43433_0746.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	NTQFEVS.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	ABAU360910:BAV0729-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_BORA1

Accession

Primary (citable) accession number: Q2KX12

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program