Reviewed, UniProtKB/Swiss-Prot Q2KW92 (PPNK_BORA1)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase
      Short name=Poly(P)/ATP NAD kinase
    EC=2.7.1.23

Gene names

Name:	ppnK
Ordered Locus Names:	BAV2722

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	299 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 299	299	Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361		PRO_1000005390

Sequences

	Sequence		Length	Mass (Da)
	Q2KW92-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 233ACBDC1A282217	FASTA	299	32,320
	10 20 30 40 50 60 MHFPIVALIG RYQDTGLDAP LRALAAMLTQ AGRRVLVDAD TARNTAVHEY PVATMQEIGE 70 80 90 100 110 120 SASLAVVMGG DGTVLGVARH LAPYGVPLIG INHGRLGFIT DIPLQDAHDA LARVLDGNFQ 130 140 150 160 170 180 IEERMLLQGS VWRGDALMYT ASALNDVVLN RAGRGGMIEM RVELDGVYMY TQRADGLIIA 190 200 210 220 230 240 TPTGSTAYAL SANGPLLHPG LNAMVLVPVA PQSLSNRPIV IPDTGVLNMT LTAIGRVETG 250 260 270 280 290 ASAHFDMQTW SDLQLGDRIT VQRAPHTARL VHPQGYSFFS TLRRKLHWNQ MPQVSDNIE

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM167904 Genomic DNA. Translation: CAJ50333.1.
RefSeq	YP_787220.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6267205.
GenomeReviews	Gene locus BAV2722 in contig AM167904_GR.
KEGG	bav:BAV2722.
NMPDR	fig|521.1.peg.330.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2KW92.
OMA	ASENNDW.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK_BORA1

Accession

Primary (citable) accession number: Q2KW92

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	March 7, 2006
Last modified:	November 3, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)