Q2KVX0 (SYQ_BORA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamine--tRNA ligase
EC=6.1.1.18

Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS

Gene names

Name:	glnS
Ordered Locus Names:	BAV2787

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella › Bordetella avium

Protein attributes

Sequence length	586 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glutaminyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro glutamyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP glutamine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 586	586	Glutamine--tRNA ligase HAMAP-Rule MF_00126		PRO_1000095478
Regions
	Motif	58 – 68	11	"HIGH" region HAMAP-Rule MF_00126
	Motif	301 – 305	5	"KMSKS" region HAMAP-Rule MF_00126
Sites
	Binding site	304	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2KVX0 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 0791D6E9BCC7E191	FASTA	586	66,544
	10 20 30 40 50 60 MTQTTAPHAA SNYLRNIIED DLAANRFQGK RWAGKPGPAS MQASGLPDPA RIRTRFPPEP 70 80 90 100 110 120 NGYLHIGHAK SICVNFGIAK EFGGVCHLRF DDTNPEKEDQ EYVDAIIEAV RWLGFDWNTD 130 140 150 160 170 180 GNNNLYFASD YFEFMYEFAE ALIEAGHAFV DEQSADDIRA QRGTLTEPGR NSPFRDRPAA 190 200 210 220 230 240 ESLTRLREMR DGKHPDGSLV LRARIDMASP NINLRDPVMY RVRHAAHHRT GDKWCIYPMY 250 260 270 280 290 300 SWAHPVEDAL EGITHSICTL EFEDQRPFYD WILARLADLG KLARPLPRQY EFSRLNMSYI 310 320 330 340 350 360 VTSKRKLLQL VREGYVDGWD DPRMPTLFGL RRRGYTASAI RLFCDRTAVS KSDSRIDYSL 370 380 390 400 410 420 LEQAVRDDLD PGTTRSVAVL DPLKLVITNY PKDQTEVCKA PRNPHDPEAG QREFPFSREL 430 440 450 460 470 480 WIERDDFREE APKKYFRLFP GNLVRLKYGY VVRCTGFTKD EAGNITEVQA EYLPDTKSGT 490 500 510 520 530 540 PGADSVKVKG NITWVSAAHA VPAEVRLYDR LFADPHPDGG DKDFLACLNP NSIQTVQAWL 550 560 570 580 EPGTRAEPGA TWQFERLGYF TVDSKDSSPE APVLNRIVTL KDSWAA

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 197N.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM167904 Genomic DNA. Translation: CAJ50398.1.
RefSeq	YP_787285.1. NC_010645.1.
3D structure databases
ProteinModelPortal	Q2KVX0.
SMR	Q2KVX0. Positions 11-583.
ModBase	Search...
Protein-protein interaction databases
STRING	360910.BAV2787.
Proteomic databases
PRIDE	Q2KVX0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6266199.
KEGG	bav:BAV2787.
PATRIC	21131863. VBIBorAvi43433_2819.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0008.
HOGENOM	HOG000259232.
KO	K01886.
OMA	RMPTIAG.
ProtClustDB	PRK05347.
Family and domain databases
Gene3D	1.10.1160.10. 1 hit. 2.40.240.10. 2 hits. 3.40.50.620. 2 hits.
HAMAP	MF_00126. Gln_tRNA_synth.
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR004514. Gln-tRNA-synth_Ib. IPR022861. Gln_tRNA_ligase_bac. IPR000924. Glu/Gln-tRNA-synth_Ib. IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl. IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom. IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd. IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl. IPR011035. Ribosomal_L25/Gln-tRNA_synth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
PANTHER	PTHR10119. PTHR10119. 1 hit.
Pfam	PF00749. tRNA-synt_1c. 1 hit. PF03950. tRNA-synt_1c_C. 1 hit. [Graphical view]
PRINTS	PR00987. TRNASYNTHGLU.
SUPFAM	SSF50715. Ribosomal_L25rel. 1 hit.
TIGRFAMs	TIGR00440. glnS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYQ_BORA1

Accession

Primary (citable) accession number: Q2KVX0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	March 7, 2006
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program