Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q2KTT0 (HIS3_BORA1)

Last modified June 16, 2009. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Phosphoribosyl-AMP cyclohydrolase
      Short name=PRA-CH
    EC=3.5.4.19
Gene names
Name: hisI
Ordered Locus Names: BAV3320
OrganismBordetella avium (strain 197N) [Complete proteome] [HAMAP]
Taxonomic identifier360910 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeBordetella

Protein attributes

Sequence length134 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

1-(5-phosphoribosyl)-AMP + H2O = 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide. HAMAP MF_01021

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9. HAMAP MF_01021

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the PRA-CH family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Histidine biosynthesis
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processhistidine biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionphosphoribosyl-AMP cyclohydrolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 134134Phosphoribosyl-AMP cyclohydrolase HAMAP MF_01021
PRO_1000063390

Sequences

Sequence LengthMass (Da)Tools
Q2KTT0-1 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 4D5DACC40E478E89

FASTA13415,013
        10         20         30         40         50         60 
MSTEPDWMAD VVFDADGLIP AIAQDAENGQ ILMVAWMNRE SLAETAATGR AVYWSRSRKK 

        70         80         90        100        110        120 
LWRKGEESGH AQQVHELRLD CDGDVILLKV HQNGGIACHT GRASCFYRRL DGTSQRAAWV 

       130 
TVDPVLKDPE LIYK 

« Hide

References

[1]"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction."
Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M.
J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

AM167904 Genomic DNA. Translation: CAJ50930.1.
RefSeqYP_787815.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6267176.
GenomeReviewsGene locus BAV3320 in contig AM167904_GR.
KEGGbav:BAV3320.
NMPDRfig|521.1.peg.1945.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ2KTT0.
OMAQ2KTT0. LWLKGES.

Family and domain databases

HAMAPMF_01021.
[Tree]
InterProIPR002496. PRA_CycHdrlase.
[Graphical view]
PfamPF01502. PRA-CH. 1 hit.
[Graphical view]
ProDomPD002610. PRA_cyclohydro. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameHIS3_BORA1
AccessionPrimary (citable) accession number: Q2KTT0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 7, 2006
Last modified: June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents