Reviewed, UniProtKB/Swiss-Prot Q2KTN9 (SYR_BORA1)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	BAV3361

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	561 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 561	561	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_0000241992
Regions
	Motif	129 – 139	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q2KTN9-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: B606CF5844884694	FASTA	561	61,604
	10 20 30 40 50 60 MLPEQQQHLI SLLARAVAGI LPEASPDILL ERPKVAAHGD VATNVAMQLA KPAKRNPREL 70 80 90 100 110 120 AQGIVDALLA DPQARAIVDS AEIAGPGFIN LRFTAQARQA VVAAVSAQGA AFGRAARRDE 130 140 150 160 170 180 KVLVEFVSAN PTGPLHVGHA RQAALGDAIC RLFDASGWDV TREFYYNDAG NQIQNLAISV 190 200 210 220 230 240 QARARGIGPD APEWPADGYK GDYIADIARD YLAQASVQAA DGEPVQASGN IDDLEDIRAF 250 260 270 280 290 300 AVAYLRREQD LDLQAFGLKF DNFFLESSLY TSGRVERTVE TLIAKGHTYE QDGALWLRTT 310 320 330 340 350 360 ELGTGDDKDR VMRKSEGGYT YFVPDVAYHL AKWERGFHHA INIQGSDHHG TVARVRAGLQ 370 380 390 400 410 420 GLEEGIPKEF PAYVLHKMVK VMRGGEEVKI SKRAGSYVTM RDLIEWVGRD AVRYFLIQRR 430 440 450 460 470 480 ADTEFVFDID LALSKSDENP VYYIQYAHAR ICSMIASSGL DDATIAAADA ARLTAPSEFA 490 500 510 520 530 540 LMQRLAEFPN VVKLAAQELA PHHIAFWLRD CASDFHGWYN AERVLVDDEG LKQARLRLAA 550 560 TTRQVLANGL ALLGVTALER M

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM167904 Genomic DNA. Translation: CAJ50971.1.
RefSeq	YP_787856.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6266525.
GenomeReviews	Gene locus BAV3361 in contig AM167904_GR.
KEGG	bav:BAV3361.
NMPDR	fig|521.1.peg.1913.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2KTN9.
OMA	Q2KTN9. ADHHGYV.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BORA1

Accession

Primary (citable) accession number: Q2KTN9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	March 7, 2006
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)