Q2KTN7 (DSBA_BORA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Thiol:disulfide interchange protein DsbA

Gene names

Name:	dsbA
Ordered Locus Names:	BAV3363

Organism

Bordetella avium (strain 197N) [Complete proteome] [HAMAP]

Taxonomic identifier

360910 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	209 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins By similarity.
Subcellular location	Periplasm By similarity.
Sequence similarities	Belongs to the thioredoxin family. DsbA subfamily. Contains 1 thioredoxin domain.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Redox-active center Signal
PTM	Disulfide bond
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	protein disulfide oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 27	27	Potential
	Chain	28 – 209	182	Thiol:disulfide interchange protein DsbA		PRO_0000245629
Regions
	Domain	28 – 165	138	Thioredoxin
Amino acid modifications
	Disulfide bond	57 ↔ 60		Redox-active By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2KTN7 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 8C723D9C8B9A8D56	FASTA	209	22,767
	10 20 30 40 50 60 MLSSSISRLL AAAALAATTF FAPASHAEGN AYVTLSPALP SDTPGKIEVL EFFAYTCPHC 70 80 90 100 110 120 AAIEPMVEDW AKTKPEDVVL KQVPIAFNAG MKPLQQLYYT LMALDRPDLH IKVFNAIHGE 130 140 150 160 170 180 RKRLFDKKAM GDWVASQGVD RAKFDAVFDS FSVQTQVQRA NQLAEAYRID GTPSFGVGGK 190 200 FLTSPVLAGN SYEGAIKEIN KLIPMARAK

References

[1]

"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction." Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M. J. Bacteriol. 188:6002-6015(2006) [PubMed: 16885469] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 197N.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM167904 Genomic DNA. Translation: CAJ50973.1.
RefSeq	YP_787858.1. NC_010645.1.
3D structure databases
ProteinModelPortal	Q2KTN7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2KTN7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6266526.
GenomeReviews	Gene locus BAV3363 in contig AM167904_GR.
KEGG	bav:BAV3363.
NMPDR	fig|521.1.peg.1912.
PATRIC	21133055. VBIBorAvi43433_3402.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG680642.
OMA	THEALYA.
ProtClustDB	CLSK919918.
Enzyme and pathway databases
BioCyc	ABAU360910:BAV3363-MONOMER.
Family and domain databases
InterPro	IPR001853. DSBA-like_thioredoxin_dom. IPR023205. Thiol:disulphide_interchange. IPR012336. Thioredoxin-like_fold. IPR017937. Thioredoxin_CS. IPR013766. Thioredoxin_domain. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 2 hits.
KO	K03673.
Pfam	PF01323. DSBA. 1 hit. PF00085. Thioredoxin. 1 hit. [Graphical view]
PIRSF	PIRSF001488. Tdi_protein. 1 hit.
SUPFAM	SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS00194. THIOREDOXIN_1. 1 hit. PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DSBA_BORA1

Accession

Primary (citable) accession number: Q2KTN7

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2006
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program